Information for the public

Neratinib (Nerlynx) is available on the NHS. It is a possible treatment for hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-positive early breast cancer, after surgery.

To get neratinib, you must have finished taking trastuzumab (Herceptin) within the last year. Also, if you had chemotherapy before your surgery you can only have neratinib if the chemotherapy didn’t fully shrink the cancer. If you have had other treatments that target HER2 you may not be able to have neratinib.

If you are not eligible for neratinib but are already taking it, you should be able to continue until you and your doctor decide when best to stop.

Is this treatment right for me?

Your healthcare professionals should give you clear information, talk with you about your options and listen carefully to your views and concerns. Your family can be involved too, if you wish. Read more about making decisions about your care.

Questions to think about

  • How well does it work compared with other treatments?
  • What are the risks or side effects? How likely are they?
  • How will the treatment affect my day-to-day life?
  • What happens if the treatment does not work?
  • What happens if I do not want to have treatment? Are there other treatments available?

Information and support

The NHS website may be a good place to find out more about breast cancer in women and men.

These organisations can give you advice and support:

You can also get support from your local Healthwatch.

NICE is not responsible for the quality or accuracy of any information or advice provided by these organisations.

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