Information for the public

Berotralstat (Orladeyo) is available on the NHS as a possible treatment for preventing recurrent attacks of hereditary angioedema in people 12 years and older. This is only if:

  • they have at least 2 attacks per month
  • treatment is stopped if the number of attacks per month does not reduce by at least 50% after 3 months.

If you are not eligible for berotralstat but are already having it, you should be able to continue until you and your doctor decide when best to stop.

Is this treatment right for me?

Your healthcare professionals should give you clear information, talk with you about your options and listen carefully to your views and concerns. Your family can be involved too, if you wish. Read more about making decisions about your care.

Questions to think about

  • How well does it work compared with other treatments?
  • What are the risks or side effects? How likely are they?
  • How will the treatment affect my day-to-day life?
  • What happens if the treatment does not work?
  • What happens if I do not want to have treatment? Are there other treatments available?

Information and support

The NHS website may be a good place to find out more.

This organisation can give you advice and support: HAE UK, 07975 611787

You can also get support from your local Healthwatch.

NICE is not responsible for the quality or accuracy of any information or advice provided by these organisations.

ISBN: 978-1-4731-4294-7

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