Apalutamide with androgen deprivation therapy for treating hormone-sensitive metastatic prostate cancer

2.1 Apalutamide (Erleada, Janssen) is indicated 'in adult men for the treatment of metastatic hormone-sensitive prostate cancer (mHSPC) in combination with androgen deprivation therapy'.

2.2 The dosage schedule is available in the summary of product characteristics.

2.3 The price for apalutamide is £2,735 per pack of 112 tablets, each containing 60 mg of the active ingredient (excluding VAT; BNF online, March 2021). The company has a commercial arrangement (simple discount patient access scheme). This makes apalutamide available to the NHS with a discount. The size of the discount is commercial in confidence. It is the company's responsibility to let relevant NHS organisations know details of the discount.