Information for the public
Upadacitinib (RINVOQ) is available on the NHS as a possible treatment for moderately to severely active Crohn’s disease in adults if:
- they have had a previous biological treatment that has not worked well enough, has stopped working or was not tolerated, or
- they cannot have tumour necrosis factor (TNF)-alpha inhibitors.
If you are not eligible for upadacitinib but are already having it, you should be able to continue until you and your doctor decide when it is best to stop.
Is this treatment right for me?
Your healthcare professionals should give you clear information, talk with you about your options and listen carefully to your views and concerns. Your family can be involved too, if you wish. See our webpage on making decisions about your care.
Questions to think about
- How well does it work compared with other treatments?
- What are the risks or side effects? How likely are they?
- How will the treatment affect my day-to-day life?
- What happens if the treatment does not work?
- What happens if I do not want to have treatment? Are there other treatments available?
Information and support
The NHS webpage on Crohn’s disease may be a good place to find out more.
Crohn's and Colitis UK (0300 222 5700) can give you advice and support.
You can also get support from your local Healthwatch.
NICE is not responsible for the quality or accuracy of any information or advice provided by these organisations.
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