NICE process and methods

About this manual

About this manual

This manual describes the methods used in the development of NICE guidelines. It will be updated as described in section 1.5. It will replace 'The guidelines manual' (published 2009).

Citing this document: National Institute for Health and Clinical Excellence (November 2012) The guidelines manual. London: National Institute for Health and Clinical Excellence. Available from:

Nothing in this manual shall restrict any disclosure of information by NICE that is required by law (including in particular but without limitation the Freedom of Information Act 2000).

Produced by the National Institute for Health and Clinical Excellence
First issued April 2004 (updated November 2012)


Phil Alderson; Angela Bennett; Sarah Chalmers; Anne-Louise Clayton; Jane Cowl; Ben Doak; Sarah Dunsdon; Nicole Elliott; Simon Ellis; Kathryn Harrison; Ruaraidh Hill; Ann Horrell; Prashanth Kandaswamy; Caroline Keir; Kate Kelley; Lyn Knott; Judith McBride; Clifford Middleton; Moira Mugglestone; Bhash Naidoo; Norma O'Flynn; Janet Robertson; Rachel Ryle; Carlos Sharpin; Linda Sheppard; Toni Tan; Nichole Taske; Judith Thornton; Claire Turner; Maggie Westby; Craig Whittington; Sarah Willett.


© Copyright National Institute for Health and Clinical Excellence, 2012. All rights reserved. This material may be freely reproduced for educational and not-for-profit purposes. No reproduction by or for commercial organisations, or for commercial purposes, is allowed without the express written permission of NICE.

ISBN: 978-1-4731-1906-2