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    EarlyCDT Lung for assessing risk of lung cancer in solid lung nodules

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    4 Recommendations for further research

    4.1 Further research is recommended on:

    • The accuracy of EarlyCDT Lung, and the validity of the risk models used to combine EarlyCDT Lung results with the Brock and the Herder risk models.

    • The impact of EarlyCDT Lung on clinical management decisions.

    4.2 A large retrospective audit is recommended to:

    • Understand how patient and nodule characteristics impact on malignancy prevalence and disease progression.

    • Understand current practice regarding clinical management of people with intermediate-risk lung nodules.

    • Determine the clinical consequences of CT surveillance, including the likelihood of disease progression during CT surveillance.

    • Determine the likelihood and impact of unnecessary biopsy or resection of indolent and benign nodules

      If existing data on these points is limited or not routinely collected, a prospective data collection should be undertaken to obtain it.