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Avelumab for maintenance treatment of locally advanced or metastatic urothelial cancer after platinum-based chemotherapy

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2 Information about avelumab

Marketing authorisation indication

2.1 Avelumab (Bavencio, Merck Serono) is indicated 'as monotherapy for the first-line maintenance treatment of adult patients with locally advanced or metastatic urothelial cancer who are progression-free following platinum-based chemotherapy'.

Dosage in the marketing authorisation

2.2 The dosage schedule is available in the summary of product characteristics.

Price

2.3 The list price is £768.00 per 200 mg/10 ml concentrate for solution for infusion vials (excluding VAT; BNF online, accessed April 2021).

The company has a commercial arrangement. This makes avelumab available to the NHS with a discount and it would have also applied to this indication if the technology had been recommended. The size of the discount is commercial in confidence. It is the company's responsibility to let relevant NHS organisations know details of the discount.