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2 Information about selpercatinib

Marketing authorisation indication

2.1 Selpercatinib (Retsevmo, Elli Lily) is indicated for the treatment of adults with advanced RET fusion-positive non-small cell lung cancer (NSCLC) who require systemic therapy following prior treatment with immunotherapy and/or platinum-based chemotherapy'.

Price

2.3 The list price for 60 capsules of selpercatinib (80 mg) is £4,680 (excluding VAT; BNF online, accessed July 2021). The company's estimated cost for a 28‑day cycle of selpercatinib is £8,736.00.

2.4 The company has a commercial arrangement, which would have applied if the technology had been recommended.