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    Overview

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    Literature search strategy

    Databases

    Date searched

    Version/files

    Cochrane Database of Systematic Reviews – CDSR (Cochrane Library)

    24/05/2021

    Issue 4 of 12, April 2021

    Cochrane Central Database of Controlled Trials – CENTRAL (Cochrane Library)

    24/05/2021

    Issue 4 of 12, April 2021

    International HTA database

    24/05/2021

    -

    MEDLINE (Ovid)

    24/05/2021

    1946 to May 21, 2021

    MEDLINE In-Process (Ovid) & MEDLINE ePubs ahead of print (Ovid)

    24/05/2021

    May 21, 2021

    EMBASE (Ovid)

    24/05/2021

    1974 to 2021 May 21

    Trial sources searched

    • Clinicaltrials.gov

    • ISRCTN

    • WHO International Clinical Trials Registry

    Websites searched

    • National Institute for Health and Care Excellence (NICE)

    • NHS England

    • Food and Drug Administration (FDA) - MAUDE database

    • Australian Safety and Efficacy Register of New Interventional Procedures – Surgical (ASERNIP – S)

    • Australia and New Zealand Horizon Scanning Network (ANZHSN)

    • General internet search

    MEDLINE search strategy

    The MEDLINE search strategy was translated for use in the other sources.

    Number

    Search term

    1

    Lymphedema/

    2

    (lymphoed* or lymphoo* or lymphed*).tw.

    3

    (lymph* adj4 (edema* or oedema* or cyst* or fluid*)).tw.

    4

    ((nonne-milroy* or milroy* or meige*) adj4 (diseas* or syndrome*)).tw.

    5

    Lymphocele/

    6

    lymphocel*.tw.

    7

    (Lymphatic adj4 (obstruct* or disrupt* or impair* or dysfunct* or insufficien* or malfunction* or block* or compromise*)).tw.

    8

    (fluid adj4 (drain* or block* or retent* or build-up* or buildup* or accumulat*)).tw.

    9

    (subcutaneous* adj4 (adipos* or fat*) adj4 (build-up* or buildup* or disorder* or disease* or increase* or deposit* or depot* or collect*)).tw.

    10

    ((fat* or adipos*) adj4 (tissue* or cell*) adj4 (swell* or swollen or enlarge* or build-up* or buildup* or disorder* or disease*)).tw.

    11

    or/1-10

    12

    Lipectomy/

    13

    (lipectom* or lipoplast* or lipolysis or liposuction* or lipo-suction*).tw.

    14

    adipectom*.tw.

    15

    dermolipectom*.tw.

    16

    (fat* adj4 (suction* or excision* or remov*)).tw.

    17

    Adipose Tissue/su

    18

    (adipose tissue adj4 surg*).tw.

    19

    plastic surgery/

    20

    ((plastic or cosmetic or esthetic) adj4 surger*).tw.

    21

    or/12-20

    22

    11 and 21

    23

    CA-Mi Hospivac*.tw.

    24

    Vitruvian infiltration pump*.tw.

    25

    Vacusat power*.tw.

    26

    or/23-25

    27

    22 or 26

    28

    animals/ not humans/

    29

    27 not 28

    30

    limit 29 to english language

    31

    limit 30 to ed=20170302-20210531