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    Interventional procedure overview of nerve graft for corneal denervation

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    Literature search strategy

    Databases

    Date searched

    Version/files

    Cochrane Database of Systematic Reviews – CDSR (Cochrane Library)

    27/07/2021

    Issue 7 of 12, July 2021

    Cochrane Central Database of Controlled Trials – CENTRAL (Cochrane Library)

    27/07/2021

    Issue 7 of 12, July 2021

    International HTA database

    27/07/2021

    -

    MEDLINE (Ovid)

    27/07/2021

    1946 to July 26, 2021

    MEDLINE In-Process (Ovid) & MEDLINE ePubs ahead of print (Ovid)

    27/07/2021

    July 26, 2021

    EMBASE (Ovid)

    27/07/2021

    1974 to 2021 July 26

    Trial sources searched

    • Clinicaltrials.gov

    • ISRCTN

    • WHO International Clinical Trials Registry

    Websites searched

    • National Institute for Health and Care Excellence (NICE)

    • NHS England

    • Food and Drug Administration (FDA) - MAUDE database

    • Australian Safety and Efficacy Register of New Interventional Procedures – Surgical (ASERNIP – S)

    • Australia and New Zealand Horizon Scanning Network (ANZHSN)

    • General internet search

    MEDLINE search strategy

    The MEDLINE search strategy was translated for use in the other sources.

    Number

    Search term

    1

    exp Cornea/

    2

    exp Corneal Diseases/

    3

    Trigeminal Nerve Diseases/

    4

    Trigeminal Nerve/

    5

    Ophthalmic Nerve/

    6

    (cornea* adj4 (anaesthesia* or denervation* or dystroph*)).tw.

    7

    (neurotrophic adj4 (keratopathy* or keratiti*)).tw.

    8

    ((cornea* or ophthalmic or trigeminal or cranial nerve) adj4 (impair* or disease* or disorder* or neuropath* or dysfunction* or abnormal*)).tw.

    9

    (cornea* adj4 (endothelium or epithelium) adj4 (defect* or deficit* or abnormal* or breakdown or break-down or deteriorat*)).tw.

    10

    or/1-9

    11

    Nerve Regeneration/

    12

    Nerve Transfer/

    13

    Cornea* neuroti?ation.tw.

    14

    ((innervation or sensation*) adj4 restor*).tw.

    15

    (reinnervation* or re-innervation* or re-epitheliali?ation or reepitheliali?ation).tw.

    16

    ((Nerv* or neural) adj4 (graft* or transfer* or transplant* or crossover* or neurotization* or neurotisation* or donor* or regenerat* or re-generat* or recover* or repair*)).tw.

    17

    or/11-16

    18

    10 and 17

    19

    animals/ not humans/

    20

    18 not 19