Interventional procedure overview of intraoperative electron beam radiotherapy for locally advanced and locally recurrent colorectal cancer
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Indications and current treatment
Colorectal cancer is a common cancer. It typically occurs in people older than 50, with the risk increasing with age. About 5% to 20% of people with colorectal cancer have locally advanced disease, in which the cancer has invaded nearby tissues. After primary resection to remove the tumour, it returns in the same place in about 5% to 20% of people.
There are various treatments for colorectal cancer, including resection, chemotherapy and radiotherapy. Treatment choice depends on the type of cancer, location and staging. The radicality of resection is the most important prognostic factor for survival. Resection is referred to as:
R0, when there are clear margins around the tumour
R1, when there are microscopically involved margins
R2, when there are macroscopically involved margins or gross residual disease.
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