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    a. Has all of the relevant evidence been taken into account?

  • Question on Consultation

    b. Are the summaries of clinical and cost effectiveness reasonable interpretations of the evidence?

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    c. Are the recommendations sound and a suitable basis for guidance to the NHS?

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1 Recommendations

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2 Information about Sodium zirconium cyclosilicate

Marketing authorisation indication

2.1

Sodium zirconium cyclosilicate (Lokelma, AstraZeneca) is indicated for 'the treatment of hyperkalaemia in adult patients'.

Price

2.3

The list price of sodium zirconium cyclosilicate is £10.40 per 10-g sachet or £5.20 per 5-g sachet (BNF, October 2025)

2.4

Costs may vary in different settings because of negotiated procurement discounts.

Carbon Reduction Plan

2.5

Information on the Carbon Reduction Plan for UK carbon emissions for AstraZeneca will be included here when guidance is published.