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    Overview

    This guideline covers assessment and referral for anaphylaxis. It aims to improve the quality of care for people with suspected anaphylaxis by detailing the assessments that are needed and recommending referral to specialist allergy services.

    NICE has also produced a guideline on drug allergy.

    This guideline will update NICE guideline CG134 (published 2011, amended 2020).

    Who is it for?

    • Healthcare professionals

    • Commissioners and providers

    • People with suspected anaphylaxis and their families and carers

    What does it include?

    • the recommendations

    • the guideline context.

    New and updated recommendations

    We have updated the recommendations on period of observation following treatment for suspected anaphylaxis to bring them in line with guidance from the Resuscitation Council UK.

    We have also updated 2 recommendations on admission and referral for consistency with the new recommendations on observation following treatment and to incorporate advice from the MHRA and the British Society for Allergy and Clinical Immunology (BSACI), on the provision of autoinjectors. You are invited to comment on the new and updated recommendations by answering the questions on the consultation page. New recommendations are marked as [2026].

    We have also made some minor changes to the structure of the guideline, including introducing sub-headings to improve navigation.

    See update information for a full explanation of what is being updated.

    This guideline covers assessment and referral for anaphylaxis. It aims to improve the quality of care for people with suspected anaphylaxis by detailing the assessments that are needed and recommending referral to specialist allergy services.

    NICE has also produced a guideline on drug allergy.

    This guideline will update NICE guideline CG134 (published 2011, amended 2020).

    Who is it for?

    • Healthcare professionals

    • Commissioners and providers

    • People with suspected anaphylaxis and their families and carers

    What does it include?

    • the recommendations

    • the guideline context.

    New and updated recommendations

    We have updated the recommendations on period of observation following treatment for suspected anaphylaxis to bring them in line with guidance from the Resuscitation Council UK.

    We have also updated 2 recommendations on admission and referral for consistency with the new recommendations on observation following treatment and to incorporate advice from the MHRA and the British Society for Allergy and Clinical Immunology (BSACI), on the provision of autoinjectors. You are invited to comment on the new and updated recommendations by answering the questions on the consultation page. New recommendations are marked as [2026].

    We have also made some minor changes to the structure of the guideline, including introducing sub-headings to improve navigation.

    See update information for a full explanation of what is being updated.