Summary
23. Disease-specific reference models and case extensions can provide several benefits to NICE, companies and the health and care system, through greater consistency in methods, more efficient use of time, and greater transparency in decision making (see the appendix).
24. Implementing reference models has challenges, as they are resource-intensive to build and maintain, and there are barriers to incorporating them into existing NICE processes. NICE will explore reducing these barriers, including by exploring new information technologies and collaborating with HTA organisations internationally.
25. This position statement describes how NICE will develop and use disease-specific reference case extensions across its guidance production programmes. Disease-specific reference case extensions are being taken forwards first in the areas of MASH and obesity.