April 2017: Recommendation 22.214.171.124 was updated in line with the more recent NICE guideline on suspected cancer: recognition and referral. This recommendation is dated . Recommendation 126.96.36.199 was removed as it was no longer needed after the changes to recommendation 188.8.131.52.
February 2015: New recommendations on dietary and lifestyle advice and pharmacological therapy were added to the section on clinical management of IBS. The guideline addendum contains details of the methods and evidence used to update these recommendations.
Recommendations are marked as , [new 2015],  and :
 indicates changes made to update the recommendation in line with more recent NICE guideline on suspected cancer: recognition and referral.
[new 2015] indicates that the evidence has been reviewed and a recommendation has been added or updated.
 indicates that the evidence has been reviewed but no change has been made to the recommended action.
 indicates that the evidence has not been reviewed since 2008.
Please note that in the 2015 update, recommendation 184.108.40.206 was added. Therefore, the recommendations that were numbered as 220.127.116.11 to 18.104.22.168 in the 2008 guideline have been renumbered as recommendations 22.214.171.124 to 126.96.36.199 in the 2015 update. The 2008 recommendation numbers have been retained in the full guideline.
Minor changes since publication
May 2022: We added a link to NICE's guideline on medicines associated with dependence or withdrawal symptoms in the section on pharmacological therapy.