2 The technology

The technology

2.1 KardiaMobile 6L (AliveCor) 6-lead, handheld, electrocardiogram (ECG) device.

The comparator

2.2 12‑lead ECG device.

Clinical need

2.3 People taking antipsychotic medication may need to have tests for cardiac abnormalities before starting treatment and at regular intervals during treatment. NICE guidelines on bipolar disorder and psychosis and schizophrenia in adults have recommendations on using antipsychotic medication. Detecting cardiac abnormalities such as prolonged QT interval can inform choice of therapy, dosing, whether to stop therapy, and potentially avoid severe cardiac events.

2.4 QT interval is usually measured using a 12‑lead ECG device to record the ECG. This needs the person to partially undress and use conductive stickers or gel on the skin to create contact with the electrodes. This can cause reluctance and distress. An ECG is recorded in primary or secondary care centres.

2.5 The KardiaMobile 6L allows ECG recording with less need for undressing and without using conductive stickers or gel. KardiaMobile 6L ECG can be recorded during a routine home visit by a community health professional. This may reduce stress and anxiety. KardiaMobile 6L is not intended for use in children.

2.6 Further details on the technology, comparator, clinical need and care pathway are in the final scope for KardiaMobile 6L for measuring QT interval in people having antipsychotic medication.

  • National Institute for Health and Care Excellence (NICE)