Suggested remit: To appraise the clinical and cost effectiveness of teclistamab within its marketing authorisation for treating relapsed or refractory multiple myeloma after 3 therapies.
 
Status In progress
Technology type Medicine
Decision Selected
Reason for decision Anticipate the topic will be of importance to patients, carers, professionals, commissioners and the health of the public to ensure clinical benefit is realised, inequalities in use addressed, and help them make the best use of NHS resources
Process STA Standard
ID number 6333

Provisional Schedule

Committee meeting 04 June 2024
Expected publication 14 August 2024

Project Team

Project lead Louise Jafferally

Email enquiries

External Assessment Group Liverpool Reviews and Implementation Group, University of Liverpool

Stakeholders

Companies sponsors Janssen-Cilag (teclistamab)
Others Department of Health and Social Care
  NHS England
Patient carer groups Blood Cancer UK
  Myeloma UK
Professional groups Association of Cancer Physicians
  Cancer Research UK
  Royal College of Pathologists
  Royal College of Physicians
  Royal College of Radiologists
  UK Myeloma Society
Associated public health groups None
Comparator companies Takeda (ixazomib) (confidentiality agreement signed, participating)
  Accord Healthcare (bortezomib) (confidentiality agreement not signed, not participating)
  Aspire Pharma (bortezomib) (confidentiality agreement not signed, not participating)
  • Baxter Healthcare Ltd (cyclophosphamide) (confidentiality agreement not signed, not participating)
  Biocon Pharma UK (lenalidomide) (confidentiality agreement not signed, not participating)
  Bristol Myers Squibb Pharmaceuticals (lenalidomide, pomalidomide) (confidentiality agreement not signed, not participating)
  Cipla EU (lenalidomide) (confidentiality agreement not signed, not participating)
  Dr Reddy's Laboratories (bortezomib) (confidentiality agreement not signed, not participating)
  Glenmark Pharmaceuticals Europe Ltd (lenalidomide) (confidentiality agreement not signed, not participating)
  Medac GmbH (bortezomib) (confidentiality agreement not signed, not participating)
  MSN Laboratories Europe (bortezomib) (confidentiality agreement not signed, not participating)
  Mylan (lenalidomide) (confidentiality agreement not signed, not participating)
  Pfizer (bortezomib) (confidentiality agreement not signed, not participating)
  Pharma& GmBH (panobinostat) (confidentiality agreement not signed, not participating)
  Piramal Critical Care (lenalidomide) (confidentiality agreement not signed, not participating)
  Ranbaxy, a Sun Pharmaceutical Company (lenalidomide) (confidentiality agreement not signed, not participating)
  Sandoz (bortezomib, lenalidomide, cyclophosphamide) (confidentiality agreement not signed, not participating)
  Sanofi (isatuximab) (confidentiality agreement not signed, not participating)
  Sun Pharmaceutical (bortezomib) (confidentiality agreement not signed, not participating)
  Teva UK (lenalidomide) (confidentiality agreement not signed, not participating)
  Thornton & Ross (bortezomib, lenalidomide) (confidentiality agreement not signed, not participating)
  Tillomed Laboratories (bortezomib) (confidentiality agreement not signed, not participating)
  Zentiva (lenalidomide) (confidentiality agreement not signed, not participating)
General commentators All Wales Therapeutics and Toxicology Centre
  British National Formulary
  Department of Health, Social Services and Public Safety for Northern Ireland
  Healthcare Improvement Scotland
  Medicines and Healthcare products Regulatory Agency
  Scottish Medicines Consortium
  Welsh Government
  Welsh Health Specialised Services Committee
Relevant research groups Institute of Cancer Research

Timeline

Key events during the development of the guidance:

Date Update
20 November 2023 Invitation to participate
09 October 2023 - 30 October 2023 Consultation on suggested remit, draft scope and provisional stakeholder list of consultees and commentators
09 October 2023 In progress. Draft Scope consultation
06 October 2023 Awaiting development. Status change linked to Topic Selection Decision being set to Selected
27 September 2023 This appraisal is expected to start during early October 2023 with a consultation on the draft scope. It is then anticipated that the final scope will be released along with an invitation to participate in the evaluation during mid-November 2023.

For further information on our processes and methods, please see our CHTE processes and methods manual