Suggested remit: To appraise the clinical and cost effectiveness of epcoritamab with rituximab and lenalidomide for treating relapsed or refractory follicular lymphoma after 1 or more systemic treatments.

Status:
In progress
Technology type:
Medicine
Decision:
Selected
Reason for decision:
Anticipate the topic will be of importance to patients, carers, professionals, commissioners and the health of the public to ensure clinical benefit is realised, inequalities in use addressed, and help them make the best use of NHS resources
Process:
STA Standard
ID number:
6586

Provisional Schedule

Committee meeting: 1:
07 July 2026
Expected publication:
03 September 2026

Project Team

Project lead
Leena Issa

Email enquiries

If you have any queries please email TACommC@nice.org.uk

Stakeholders

Companies sponsors
AbbVie (epcoritamab)
Others
Department of Health and Social Care
 
NHS England
Patient carer groups
African Caribbean Leukaemia Trust
 
Anthony Nolan
 
Black Health Agency for Equality
 
Blood Cancer UK
 
Cancer Black Care
 
Cancer52
 
Follicular Lymphoma Foundation
 
Independent Cancer Patients Voice
 
Kevin Kararwa Leukaemia Trust
 
Leukaemia Cancer Society
 
Leukaemia Care
 
Leukaemia UK
 
Lymphoma Action
 
Macmillan Cancer Support
 
Maggie’s Centres
 
Marie Curie
 
South Asian Health Foundation
 
Specialised Healthcare Alliance
 
Tenovus Cancer Care
Professional groups
Association of Cancer Physicians
 
British Geriatrics Society
 
British Institute of Radiology
 
British Oncology Pharmacy Association
 
British Psychosocial Oncology Society
 
British Society for Haematology
 
British Society of Interventional Radiology
 
British Transplantation Society
 
Cancer Research UK
 
NHS Blood and Transplant
 
Royal College of General Practitioners
 
Royal College of Nursing
 
Royal College of Pathologists
 
Royal College of Physicians
 
Royal College of Radiologists
 
Royal Pharmaceutical Society
 
Royal Society of Medicine
 
Society and College of Radiographers
 
UK Clinical Pharmacy Association
 
UK Oncology Nursing Society
Associated public health groups
Public Health Wales
 
UK Health Security Agency
Comparator companies
AbbVie (epcoritamab)
 
Amarox (lenalidomide)
 
Biocon Pharma (lenalidomide)
 
Bristol Myers Squibb (lenalidomide)
 
Celltrion Healthcare (rituximab)
 
Dr Reddy’s Laboratories (bendamustine, rituximab)
 
Grindeks Kalceks UK (lenalidomide)
 
Incyte Biosciences UK (tafasitamab)
 
Mylan (lenalidomide)
 
Pfizer (rituximab)
 
Roche (obinutuzumab, rituximab)
 
Sandoz (lenalidomide, rituximab)
 
Seacross Pharmaceuticals (bendamustine)
 
Sun Pharma (lenalidomide)
 
Teva UK (lenalidomide)
 
Thornton & Ross (lenalidomide)
General commentators
All Wales Therapeutics and Toxicology Centre
 
Allied Health Professionals Federation
 
Board of Community Health Councils in Wales
 
British National Formulary
 
Care Quality Commission
 
Department of Health - Northern Ireland
 
Healthcare Improvement Scotland
 
Medicines and Healthcare products Regulatory Agency
 
National Association of Primary Care
 
National Pharmacy Association
 
NHS Confederation
 
NHS Wales Joint Commissioning Committee
 
Scottish Medicines Consortium
 
Welsh Government
Relevant research groups
Cochrane Haematology Group
 
Genomics England
 
Institute of Cancer Research
 
Leukaemia Busters
 
Lymphoma Research Trust
 
MRC Clinical Trials Unit
 
National Institute for Health Research

Timeline

Key events during the development of the guidance:

Date Update
24 November 2025 Invitation to participate
17 September 2025 - 15 October 2025 Consultation on suggested remit, draft scope and provisional stakeholder list of consultees and commentators
02 October 2025 To appraise the clinical and cost effectiveness of Rituximab + Lenalidomide + Epcoritamab within its marketing authorisation for treating follicular lymphoma
17 September 2025 In progress. Scoping commenced.
15 May 2025 Awaiting development. Status change linked to Topic Selection Decision being set to Selected

For further information on our processes and methods, please see our CHTE processes and methods manual