Long-term safety of assisted reproductive technologies

1.54 Long-term health outcomes of ovulation induction and ovarian stimulation

1.54.1

Give people who are considering ovulation induction or ovarian stimulation up-to-date information about the long-term health outcomes of these treatments. [2013]

1.54.2

Inform people who are offered ovulation induction or ovarian stimulation that:

  • no direct association has been found between these treatments and invasive cancer and

  • no association has been found in the short to medium term between these treatments and adverse outcomes (including cancer) in children born from ovulation induction and

  • information about long-term health outcomes is still awaited. [2013]

1.54.3

Limit the use of ovulation induction or ovarian stimulation agents to the lowest effective dose and duration of use. [2013]

1.55 Long-term health outcomes and safety of in vitro fertilisation (IVF)

1.55.1

Give people who are considering IVF treatment, with or without intracytoplasmic sperm injection (ICSI), up to-date information about the long-term health outcomes (including the consequences of multiple pregnancy) of these treatments. [2013]

1.55.2

Inform people that, while the absolute risks of long-term adverse outcomes of IVF treatment, with or without ICSI, are low, a small increased risk of borderline ovarian tumours cannot be excluded. [2013]

1.55.3

Inform people who are considering IVF treatment that the absolute risks of long-term adverse outcomes in children born as result of IVF are low. [2013]

1.55.4

Limit drugs used for controlled ovarian stimulation in IVF treatment to the lowest effective dose and duration of use. [2013]