Update information

March 2026: This guideline partially updates and replaces NICE guideline CG156 (published 2013). We have removed the recommendations on hypothalamic-pituitary-ovarian dysfunction (predominantly PCOS) because NICE is developing a guideline on polycystic ovary syndrome (PCOS). For more information, see the guideline's development page on the NICE website.

Recommendations are marked [2026] if the evidence has been reviewed.

We have also made some changes without an evidence review. These are marked [2004, amended 2026] or [2013, amended 2026].

Recommendations labelled [2004] or [2013] last had an evidence review in 2004 or 2013, respectively.

ISBN: 978-1-4731-9360-4