2 Information about zanidatamab

Marketing authorisation indication

2.1

Zanidatamab (Ziihera, Jazz Pharmaceuticals) as monotherapy is indicated for 'the treatment of adults with unresectable locally advanced or metastatic HER2-positive (IHC3+) biliary tract cancer (BTC) previously treated with at least one prior line of systemic therapy'.

Dosage in the marketing authorisation

Price

2.3

The list price per pack of 2 vials of 300 mg zanidatamab is currently confidential.

2.4

The company has a commercial arrangement. This makes zanidatamab available to the NHS with a discount. The size of the discount is commercial in confidence.

Sustainability

2.5

For information, Jazz Pharmaceuticals did not disclose its Carbon Reduction Plan for UK carbon emissions.