4 Appraisal Committee members and NICE project team

Appraisal Committee members

The Appraisal Committee is a standing advisory committee of NICE. Its members are appointed for a 3-year term. A list of the Committee members who took part in the discussions for this appraisal appears below. The Appraisal Committee meets 3 times a month except in December, when there are no meetings. The Committee membership is split into 3 branches, each with the chair and a vice chair. Each branch considers its own list of technologies and ongoing topics are not moved between the branches.

Committee members are asked to declare any interests in the technology to be appraised. If it is considered there is a conflict of interest, the member is excluded from participating further in that appraisal.

The minutes of each Appraisal Committee meeting, which include the names of the members who attended and their declarations of interests, are posted on the NICE website.

Professor David Barnett
Professor of Clinical Pharmacology, University of Leicester

Dr David W Black
Director of Public Health, Chesterfield PCT

Mr Brian Buckley
Chairman, Incontact

Professor Mike Campbell
Professor of Medical Statistics, University of Sheffield

Dr Carol Campbell
Senior Lecturer, University of Teeside

Dr Peter Clark
Consultant Medical Oncologist, Clatterbridge Centre for Oncology, Merseyside

Ms Jude Cohen
Manager of Resources and Administration, Council for Psychotherapy (UKCP)

Dr Christine Davey
Senior Researcher, North Yorkshire Alliance R and D Unit

Dr Mike Davies
Consultant Physician, Manchester Royal Infirmary

Mr Richard Devereaux-Phillips
Public Affairs Manager, Medtronic Ltd

Dr Rachel A Elliott
Clinical Senior Lecturer, University of Manchester

Mrs Eleanor Grey
Lay Member

Dr Dyfrig Hughes
Senior Research Fellow in Pharmacoeconomics, Centre for the Economics of Health and Policy in Health, University of Wales, Bangor

Dr Catherine Jackson
Clinical Lecturer in Primary Care Medicine, Alyth Health Centre

Dr Peter Jackson
Clinical Pharmacologist, University of Sheffield

Professor Peter Jones
Professor of Statistics and Dean Faculty of Natural Sciences, Keele University

Ms Rachel Lewis
Nurse Advisor to the Department of Health

Dr Damien Longson
Consultant in Liaison Psychiatry, North Manchester General Hospital

Professor Jonathan Michaels
Professor of Vascular Surgery, University of Sheffield

Dr Eugene Milne
Deputy Medical Director, North East Strategic Health Authority

Dr Simon Mitchell
Consultant Neonatal Paediatrician, St Mary's Hospital, Manchester

Dr Martin J Price
Head of Outcomes Research, Janssen-Cilag Ltd

Mr Miles Scott
Chief Executive, Bradford Teaching Hospitals NHS Foundation Trust

Professor Mark Sculpher
Professor of Health Economics, University of York

Professor Andrew Stevens
Chair of Appraisal Committee C

Dr Cathryn Patricia Thomas
Senior Lecturer, Department of Primary Care and General Practice

NICE project team

Each technology appraisal is assigned to a team consisting of 1 or more health technology analysts (who act as technical leads for the appraisal), a technical adviser and a project manager.

Helen Tucker
Technical Lead

Louise Longworth
Technical Adviser

Chris Feinmann
Project Manager

Sources of evidence considered by the Committee

The Evidence Review Group (ERG) report for this appraisal was prepared by Liverpool Reviews and Implementation Group (LRiG):

  • Bagust A et al Pemetrexed for the treatment of relapsed non-small cell lung cancer, September 2006.

The following organisations accepted the invitation to participate in this appraisal. They were invited to comment on the draft scope. Companies or sponsors were also invited to make written submissions. Professional or specialist, and patient or carer groups, gave their expert views on pemetrexed by providing a written statement to the Committee. Companies or sponsors, and professional or specialist, and patient or carer groups, have the opportunity to appeal against the final appraisal determination.

Company or sponsor:

  • Eli Lilly and Company Ltd.

Professional or specialist, and patient or carer groups:

  • British Thoracic Oncology Group

  • British Thoracic Society

  • Cancer Networks Pharmacists Forum

  • Cancer Research UK

  • CancerBackup

  • Department of Health

  • Roy Castle Lung Cancer Foundation

  • Royal College of Nursing

  • Royal College of Pathologists

  • Royal College of Physicians, Medical Oncology Joint Special Committee

  • Tenovus Cancer Information Centre

  • Welsh Assembly Government

Commentator organisations (did not provide written evidence and without the right of appeal):

  • British National Formulary

  • British Thoracic Oncology Group

  • MRC CTU - Lung Cancer and Mesothelioma Group

  • National Collaborating Centre for Cancer

  • NHS Quality Improvement Scotland

  • Roche Products Ltd.

  • Sanofi-Aventis

The following individuals were selected from clinical specialist and patient advocate nominations from the non-manufacturer or sponsor consultees and commentators. They gave their expert personal view on pemetrexed by providing oral evidence to the Committee.

  • Dr Jesme Baird, Director of Patient Care, nominated by the Roy Castle Lung Cancer Foundation – patient expert

  • Professor David R Ferry, Medical Oncologist, New Cross Hospital, Wolverhampton, nominated by the Royal College of Physicians – clinical specialist

  • Dr Mary O'Brien, Consultant Medical Oncologist, Institute of Cancer Research, nominated by the Institute of Cancer Research – clinical specialist

  • Dr Elizabeth Sawicka, Consultant, Princess Royal University Hospital, nominated by The British Thoracic Society – clinical specialist