6 Recommendations for further research

6.1 The Appraisal Committee considered that further research into the effectiveness of anti-VEGFs in wet AMD could include studies:

  • about the cost effectiveness of ranibizumab compared with bevacizumab

  • to investigate the long-term effects of anti-VEGFs in patients with AMD, including effects on visual acuity, anatomical damage to the macula, quality of life and adverse events

  • to establish the appropriate duration and optimal treatment regimen in terms of frequency of injections.

  • National Institute for Health and Care Excellence (NICE)