6 Recommendations for further research
6.1 The Appraisal Committee considered that further research into the effectiveness of anti-VEGFs in wet AMD could include studies:
about the cost effectiveness of ranibizumab compared with bevacizumab
to investigate the long-term effects of anti-VEGFs in patients with AMD, including effects on visual acuity, anatomical damage to the macula, quality of life and adverse events
to establish the appropriate duration and optimal treatment regimen in terms of frequency of injections.