pills split into two

Our guidance and advice to help manage common infections and tackle antimicrobial resistance.

We've been asked by the Department of Health to develop evidence-based, clinical syndrome specific guidance and advice to help slow the development of antimicrobial resistances.


Our guidelines offer evidence-based antimicrobial prescribing information for all care settings.

They focus on bacterial infections and appropriate antibiotic use. Each guideline topic features a visual summary of the recommendations, a guideline and an evidence review.

The visual summary is an overview of the guideline recommendations. It includes a prescribing table to support shared antimicrobial prescribing decisions in line with a health professional’s own clinical judgement.

summary of our recommendations on sinusitis   summary of our recommendations on sinusitis

An example of the draft visual summary for our sinusitis guideline

Sinusitis (acute)

summary of our recommendations on sinusitis

Published: 31 October 2017

Sore throat (acute)

summary of our recommendations on Sore throat

Published: 26 January 2018

Otitis media (acute)

summary of our recommendations on Otitis media

Published: 27 March 2018


Our antimicrobial evidence summaries provide commissioners, providers and health professionals with a summary of the best available evidence for antimicrobials. 

In development

We are currently developing guideline recommendations on the following topics:

Why is our guidance and advice needed?

The World Health Organization states that 'antimicrobial resistance occurs when microorganisms such as bacteria, viruses, fungi and parasites change in ways that render the medications used to cure the infections they cause ineffective'.

Resistance to antimicrobials is complex and increasing. Combined with a lack of new antimicrobial medicines, there is a growing risk that infections may not be treatable in the future. 

The Department of Health asked us to develop guidelines to help slow antimicrobial resistance. These guidelines are evidence-based and clinical syndrome specific. 

Read more about the importance of antimicrobial resistance at Health matters: antimicrobial resistance.

photograph of Tessa Lewis
When we as health professionals are discussing treatments for common infections with patients, it is important to talk about the benefits and harms of prescribing antibiotics, including the risks of antimicrobial resistance and the threat this poses to public healthTessa Lewis, GP and Chair of the managing common infections advisory committee

How we develop guidance and advice

Antimicrobial prescribing guidelines

Find out how we develop antimicrobial prescribing guidance in the:

The scope sets out the remit for the programme:

Evidence summaries

Find out how we develop our advice in the:


Get involved

Antimicrobial news at NICE

New guidance will help combat drug resistant urinary tract infections, says NICE

New guidance will help combat drug resistant urinary tract infections, says NICE

NICE has published new guidance to help healthcare professionals optimise the treatment of urinary tract infections (UTIs).

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Most common ear infections should not be treated with antibiotics, says NICE

Use paracetamol to relieve a sore throat rather than antibiotics

The majority of sore throats do not need antibiotics and medicated lozenges may only help to reduce pain by a small amount, NICE says.

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View all our latest news on antimicrobials and antibiotics