The following is a list of technologies with approved Patient Access Schemes, recommended by NICE for use in the NHS.

TA Ref Treatment Indication Company Type
TA129 Bortezomib (Velcade) Multiple myeloma JC Response scheme
TA155 Ranibizumab (Lucentis) Macular degeneration (Acute wet AMD) Novartis Simple discount
TA169 Sunitinib (Sutent) Renal cell carcinoma Pfizer Free stock
TA171 Lenalidomide (Revlimid) Multiple myeloma Celgene Dose cap
TA176 Cetuximab (Erbitux) Metastatic colorectal cancer (first Line) Merck S. Rebate
TA179 Sunitinib (Sutent) Gastrointestinal stromal tumour Pfizer Free stock
TA185 Trabectedin (Yondelis) Advanced soft tissue sarcoma PharmaMar Dose cap
TA186 Certolizumab pegol (Cimzia) Rheumatoid arthritis UCB Free initial stock
TA192 Gefitinib (Iressa) Non small cell lung cancer Astra Zeneca Single fixed price
TA215 Pazopanib (Votrient) Advanced renal cell carcinoma GSK Discount+ poss rebate
TA218 Azacitidine (Vidaza) Myelodysplastic syndromes, chronic myelomonocytic leukaemia and acute myeloid leukaemia Celgene Simple discount
TA220 Golimumab (Simponi) Psoriatic arthritis Merck Sharp & Dohme Free stock
TA221 Romiplostim (Nplate) Chronic idiopathic (immune) thrombocytopenic purpura Amgen Simple discount
TA225 Golimumab (Simponi) Rheumatoid arthritis Merck Sharp & Dohme Free stock
TA233 Golimumab (Simponi) Ankylosing spondylitis Merck Sharp & Dohme Free stock
TA235 Mifamurtide (Mepact) High grade resectable non-metastatic osteosarcoma Takeda Simple discount
TA238 Tocilizumab (RoActemra) Systemic juvenile idiopathic arthritis Roche Simple discount
TA241 Nilotinib (Tasigna) Imatinib-resistant chronic myeloid leukaemia Novartis Simple discount
TA247 Tocilizumab (RoActemra) Rheumatoid arthritis Roche Simple discount
TA251 Nilotinib (Tasigna) First-line treatment of chronic myeloid leukaemia Novartis Simple discount
TA254 Fingolimod (Gilenya) Highly active relapsing-remitting multiple sclerosis Novartis Simple discount
TA258 Erlotinib (Tarceva) First-line treatment of locally advanced or metastatic EGFR-TK mutation-positive non-small-cell lung cancer Roche Simple discount
TA265 Denosumab (Xgeva) Skeletal related events in adults with bone metastases from solid tumours Amgen Simple discount
TA268 Ipilimumab (Yervoy) Advanced melanoma, 2nd Line Bristol-Myers Squibb Simple discount
TA269 Vemurafenib (Zelboraf) Metastatic mutation positive melanoma Roche Simple discount
TA274 Ranibizumab (Lucentis) Diabetic macular odema Novartis Simple discount
TA276 Colistimethate (Colobreathe) Pseudomonas aeruginosa for adults and children over 6 with cystic fibrosis Forest Laboratories UK Simple Discount
TA276 Tobramycin (TOBI Podhaler) Pseudomonas aeruginosa for adults and children over 6 with cystic fibrosis Novartis Simple Discount
TA278 Omalizumab (Xolair) Severe persistant asthma Novartis Simple Discount
TA280 Abatacept (Orencia) Rheumatoid arthritis, polyarticular juvenile idiopathic arthritis Bristol-Myers Squibb Simple Discount
TA282 Pirfenidone (Esbriet) Mild to moderate idiopathic pulmonary fibrosis Intermune Simple Discount
TA283 Ranibizumab (Lucentis) Macular oedema secondary to retinal vein occlusion Novartis Simple Discount
TA293 Eltrombopag (Revolade) Chronic immune (idiopathic) thrombocytopenic purpura GSK

Simple

Discount

TA294 Aflibercept (Eylea) Wet age‑related macular degeneration Bayer

Simple

Discount

TA298 Ranibizumab (Lucentis) Choroidal neovascularisation secondary to pathologic myopia Novartis Simple Discount
TA301 Fluocinolone (Iluvien) Diabetic macula oedema Alimera Sciences Simple Discount
TA303 Teriflunomide (Aubagio) Active relapsing-remitting multiple sclerosis Genzyme Simple Discount
TA305 Aflibercept (Eylea) Visual impairment caused by macular oedema secondary to central retinal vein occlusion Bayer Simple Discount
TA306 Pixantrone (Pixuvri) Multiple relapsed or refractory aggressive non-Hodgkin's B-cell lymphoma CTI Life Sciences Simple Discount
TA310 Afatinib (Giotrif) Locally advanced or metastatic non-small cell lung cancer (NSCLC) with activating epidermal growth factor receptor (EGFR) Boehringer Ingelheim Limited   Simple Discount
TA316 Enzalutamide (Xtandi) Metastatic hormone-relapsed prostate cancer in adults whose disease has progressed during or after docetaxel-containing chemotherapy Astellas Simple Discount
TA319 Ipilimumab (Yervoy) Adults with previously untreated advanced (unresectable or metastatic) melanoma Bristol-Myers Squibb Simple Discount
TA320 Dimethyl fumarate (Tecfidera) Adults with active relapsing‑remitting multiple sclerosis Biogen Idec Simple Discount
TA321 Dabrafenib (Tafinlar) Unresectable or metastatic melanoma with a BRAFV600 mutation GSK Simple Discount
TA322 Lenalidomide (Revlimid) Myelodysplastic syndromes associated with an isolated deletion 5q cytogenetic abnormality Celgene Dose cap
TA329 Golimumab (Simponi) moderately to severely active ulcerative colitis Merck Sharp & Dohme Free stock
TA333 Axitinib (Inlyta) Advanced renal cell carcinoma after failure of prior systemic treatment Pfizer Simple discount
TA339 Omalizumab (Xolair) Previously treated chronic spontaneous urticaria Novartis Simple discount
TA342 Vedolizumab (Entyvio) Moderately to severely active ulcerative colitis Takeda Simple discount
TA343 Obinutuzumab (Gazyvaro) Untreated chronic lymphocytic leukaemia Roche Simple discount
TA344 Ofatumumab (Arzerra) Untreated chronic lymphocytic leukaemia Novartis Simple discount
TA346 Aflibercept (Eylea) Diabetic macular oedema Bayer Pharma
Simple discount
TA347 Nintedanib (Vargatef) Previously treated locally advanced, metastatic, or locally recurrent non‑small‑cell lung cancer Boehringer-Ingelheim
Simple discount
TA350 Secukinumab (Cosentyx) Moderate to severe plaque psoriasis Novartis Simple discount
TA352 Vedolizumab (Entyvio) Moderately to severely active Crohn's disease after prior therapy Takeda
Simple discount
TA357 Pembrolizumab (Keytruda) Advanced melanoma after disease progression with ipilimumab Merck Sharp & Dohme
Simple discount
TA358 Tolvaptan (Jinarc) Autosomal dominant polycystic kidney disease Otsuka Pharmaceuticals (UK) Limited Simple discount
TA366 Pembrolizumab (Keytruda) Advanced melanoma not previously treated with ipilimumab Merck Sharp & Dohme Simple discount
TA373 Abatacept (Orencia) Polyarticular juvenile idiopathic arthritis Bristol-Myers Squibb Simple discount
TA373 Tocilizumab (RoActemra) Polyarticular juvenile idiopathic arthritis Roche Simple discount
TA374 Erlotinib (Tarceva) Non-small-cell lung cancer that has progressed after prior chemotherapy Roche Simple discount
HST2 Elosulfase alfa (Vimizim) Mucopolysaccharidosis type IVa BioMarin Europe Ltd. Simple discount
TA375 Certolizumab pegol (Cimzia For rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed UCB Free stock (operational scheme with new indication)
TA375 Abatacept (Orencia) For rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed Bristol-Myers Squibb Simple discount (operational scheme with new indication)
TA375 Tocilizumab (RoActemra) For rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed Roche Simple discount (operational scheme with new indication)
TA375 Golimumab (Simponi) For rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed Merck Sharp & Dohme Free stock (operational scheme with new indication)
TA376 Radium-223 dichloride (Xofigo) Hormone-relapsed prostate cancer with bone metastases Bayer Simple discount (fixed price)
TA377 Enzalutamide (Xtandi) Metastatic hormone-relapsed prostate cancer before chemotherapy is indicated Astellas Pharma Ltd Simple discount (operational scheme with new indication)
TA379 Nintedanib (Ofev) Idiopathic pulmonary fibrosis Boehringer-Ingelheim Simple discount (fixed price) (operational scheme with new indication)
TA380 Panobinostat (Farydak) Multiple myeloma after at least 2 previous treatments Novartis Simple discount (fixed price)
TA381 Olaparib (Lynparza) Maintenance treatment of relapsed, platinum-sensitive, BRCA mutation-positive ovarian, fallopian tube and peritoneal cancer after response to second-line or subsequent platinum-based chemotherapy Astra Zeneca Time cap
TA383 Certolizumab pegol (Cimzia) TNF-alpha inhibitors for ankylosing spondylitis and non-radiographic axial spondyloarthritis UCB First 12 weeks free of charge, equivalent to 10 vials.
TA383 Golimumab (Simponi) TNF-alpha inhibitors for ankylosing spondylitis. Merck Sharp & Dohme Free stock (operational scheme with new indication)
TA386 Ruxolitinib (Jakavi) Disease-related splenomegaly or symptoms in adults with myelofibrosis. Novartis Simple discount
TA391 Cabazitaxel (Jevtana) Hormone-relapsed metastatic prostate cancer treated with docetaxel. Sanofi Simple discount
HST3 Ataluren (Translarna) Duchenne muscular dystrophy with a nonsense mutation in the dystrophin gene PTC Therapeutics Simple discount
TA392 Adalimumab (Humira) Moderate to severe hidradenitis suppurativa Abbvie Discounted price (this indication only)
TA393 Alirocumab (Praluent) Primary hypercholesterolaemia and mixed dyslipidaemia Sanofi Simple discount
TA394 Evolocumab (Repatha) Primary hypercholesterolaemia and mixed dyslipidaemia Amgen Simple discount
TA395 Ceritinib (Zykadia) Previously treated anaplastic lymphoma kinase positive non-small-cell lung cancer Novartis Simple discount
TA396 Trametinib (Mekinist) In combination with dabrafenib for treating unresectable or metastatic melanoma Novartis Simple discount
TA396 Dabrafenib (Tafinlar) In combination with trametinib for treating unresectable or metastatic melanoma Novartis Simple discount
TA397 Belimumab (Benlysta) Active autoantibody-positive systemic lupus erythematosus GSK Simple discount
TA401 Bosutinib (Bosulif) Previously treated chronic myeloid leukaemia Pfizer Simple discount
TA405 Trifluridine and tipiracil hydrochloride (Lonsurf) Previously treated metastatic colorectal cancer Servier Simple discount
TA406 Crizotinib (Xalkori) Untreated anaplastic lymphoma kinase-positive advanced non-small-cell lung cancer Pfizer Simple discount
TA407 Secukinumab (Cosentyx) Active ankylosing spondylitis after treatment with non-steroidal anti-inflammatory drugs or TNF-alpha inhibitors Novartis Simple discount (operational scheme with new indication)
TA409 Aflibercept (Eylea) Visual impairment caused by macular oedema after branch retinal vein occlusion Bayer Simple discount (operational scheme with new indication)
TA410 Talimogene laherparepvec (Imlygic) Unresectable metastatic melanoma Amgen Simple discount
TA412 (This guidance replaces TA376) Radium-223 dichloride (Xofigo) Hormone-relapsed prostate cancer with bone metastases Bayer Simple discount (fixed price)
TA415 Certolizumab pegol (Cimzia) Rheumatoid arthritis after inadequate response to a TNF-alpha inhibitor UCB Free stock (operational scheme with new indication)
TA417 Nivolumab (Opdivo) Previously treated advanced renal cell carcinoma in adults Bristol-Myers Squibb Simple discount
TA419 Apremilast (Otezla) Moderate to severe plaque psoriasis Celgene Simple discount
TA421 Everolimus (Afinitor) Advanced breast cancer after endocrine therapy Novartis Simple discount
TA422 Crizotinib (Xalkori) Untreated anaplastic lymphoma kinase-positive advanced non-small-cell lung cancer Pfizer Simple discount
TA423 Eribulin (Halaven) Breast cancer (locally advanced, metastatic) Eisai Simple discount
TA424 Pertuzumab (Perjeta) Neoadjuvant treatment of breast cancer Roche Simple discount
TA425 Dasatinib (Sprycel) Imatinib-resistant or intolerant chronic myeloid leukaemia Bristol-Myers Squibb Simple discount
TA425 Nilotinib (Tasigna) Imatinib-resistant or intolerant chronic myeloid leukaemia Novartis Simple discount
TA426 Dasatinib (Sprycel) Untreated chronic myeloid leukaemia Bristol-Myers Squibb Simple discount
TA426 Nilotinib (Tasigna) Untreated chronic myeloid leukaemia Novartis Simple discount
TA427 Pomalidomide (Imnovid) Multiple myeloma previously treated with lenalidomide and bortezomib Celgene Simple discount
TA428 Pembrolizumab (Keytruda) PD-L1-positive non-small-cell lung cancer after chemotherapy Merck Sharp & Dohme Simple discount
TA432 Everolimus (Afinitor) Renal cell carcinoma Novartis Simple discount (operational scheme with new indication)
TA433 Apremilast (Otezla) Active psoriatic arthritis Celgene Simple discount (operational scheme with new indication and revised discount)
HST4 Migalastat (Galafold) Fabry disease Amicus Therapeutics Simple discount
TA429 Ibrutinib (Imbruvica) Previously treated chronic lymphocytic leukaemia and untreated chronic lymphocytic leukaemia with 17p deletion or TP53 mutation Janssen Simple discount
TA431 Mepolizumab (Nucala) Severe refractory eosinophilic asthma GSK Simple discount