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    A prospective observational study of 65 patients with painful spinal metastases in the thoracolumbar spine (T1-L5) following targeted radiofrequency ablation (t-RFA) treatment with the STAR™ Tumor Ablation System, follow up 12 months, outcome measures are pain relief and quality of life improvement; location USA, study completion date March 2017; status: study was terminated due to difficulty enrolling.References

    1. Yildizhan S, Boyaci, MG, Rakip U et al. (2021) Role of radiofrequency ablation and cement injection for pain control in patients with spinal metastasis. BMC musculoskeletal disorders; 22 (1); 91.

    2. Proschek D, Kurth A, Proschek P, et al. (2009). Prospective pilot study of combined bipolar radiofrequency ablation and application of bone cement in bone metastases. Anticancer Res 29:2787–92.

    3. Nakatsuka A , Yamakado K , Takaki H et al. Percutaneous radiofrequency ablation of painful spinal tumors adjacent to the spinal cord with real-time monitoring of spinal canal temperature: a prospective study. Cardiovasc Intervent Radiol (2009) 32:70–75

    4. Gazis AN, Beuing O, Franke J et al (2014). Bipolar radiofrequency ablation of spinal tumors: predictability, safety, and outcome. Spine J; 14:604–608.

    5. Ryan A, Byrne C, Pusceddu C, Buy X, Tsoumakidou G, Filippiadis D. CIRSE Standards of Practice on Thermal Ablation of Bone Tumours. Cardiovasc Intervent Radiol. 2022 May;45(5):591-605. doi: 10.1007/s00270-022-03126-x. Epub 2022 Mar 29. PMID: 35348870; PMCID: PMC9018647

    6. Tsoumakidou G, Too CW, Koch G et al (2017). CIRSE guidelines on percutaneous vertebral augmentation. Cardiovasc Intervent Radiol; 40:331-342.

    7. Coleman R, Hadji P, Body JJ et al. (2020) Bone health in cancer: ESMO Clinical Practice Guidelines. Annals of Oncology. 31 (12), 1650–1663.

    8. Swarm RA, Paice JA, Anghelescu DL et al. (2019). NCCN Clinical Practice Guidelines in Oncology. Adult Cancer Pain Version 3.2019 J Natl Compr Canc Netw 2019;17(8):977–1007.