Interventional procedure overview of extracorporeal carbon dioxide removal for acute respiratory failure
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Methods
NICE identified studies and reviews relevant to ECCO2R for acute respiratory failure from the medical literature. The following databases were searched between the date they started to 23 February 2022: MEDLINE, PREMEDLINE, EMBASE, Cochrane Library and other databases. Trial registries and the internet were also searched (see the literature search strategy). Relevant published studies identified during consultation or resolution that are published after this date may also be considered for inclusion.
The following inclusion criteria were applied to the abstracts identified by the literature search.
Publication type: clinical studies were included with emphasis on identifying good quality studies. Abstracts were excluded if they did not report clinical outcomes. Reviews, editorials, and laboratory or animal studies, were also excluded and so were conference abstracts, because of the difficulty of appraising study methodology, unless they reported specific AEs that not available in the published literature.
People with acute respiratory failure.
Intervention or test: extracorporeal carbon dioxide removal.
Outcome: articles were retrieved if the abstract contained information relevant to the safety, efficacy, or both.
Because of the volume of papers identified, an additional inclusion criterion of n>10 participants was applied.
If selection criteria could not be determined from the abstracts the full paper was retrieved.
Potentially relevant studies not included in the main evidence summary are listed in the section on other relevant studies.
Find out more about how NICE selects the evidence for the committee.
Databases | Date searched | Version/files |
|---|---|---|
MEDLINE (Ovid) | 23/02/2022 | 1946 to February 22, 2023 |
MEDLINE In-Process (Ovid) | 23/02/2022 | 1946 to February 22, 2023 |
MEDLINE Epubs ahead of print (Ovid) | 23/02/2022 | February 22, 2023
|
EMBASE (Ovid) | 23/02/2022 | Embase 1974 to 2023 February 22 |
EMBASE Conference (Ovid) | 23/02/2022 | Embase 1974 to 2023 February 22 |
Cochrane Database of Systematic Reviews – CDSR (Cochrane Library) | 23/02/2022 | Issue 2 of 12, February 2023 |
Cochrane Central Database of Controlled Trials – CENTRAL (Cochrane Library) | 23/02/2022 | Issue 2 of 12, February 2023 |
International HTA database (INAHTA) | 23/02/2022 | - |
Trial sources searched
Clinicaltrials.gov
ISRCTN
WHO International Clinical Trials Registry
Websites searched
National Institute for Health and Care Excellence (NICE)
NHS England
Food and Drug Administration (FDA) - MAUDE database
Australian Safety and Efficacy Register of New Interventional Procedures – Surgical (ASERNIP – S)
Australia and New Zealand Horizon Scanning Network (ANZHSN)
General internet search
The following search strategy was used to identify papers in MEDLINE. A similar strategy was used to identify papers in other databases. The MEDLINE search strategy was translated for use in the other sources.
Ovid MEDLINE(R) <1946 to February 22, 2023>
1 extracorporeal circulation/ 13179
2 (extracorp* adj4 (CO2 or carbon*) adj4 remov*).tw. 434
3 ((extracorporeal or intervention*) adj4 (lung or lungs) adj4 assist*).tw. 255
4 (CO2 adj4 remov*).tw. 1375
5 (carbon* adj4 dioxide adj4 remov*).tw. 770
6 (respirat* adj4 dialysis).tw. 142
7 (ECCO2R or AVECCO2R or VVECCO2R or AVCO2R or VVCO2R or AVECO2R or PECLA).tw. 209
8 or/1-7 15298
9 Respiratory Insufficiency/ 35496
10 Respiratory Distress Syndrome/ 24179
11 Hypercapnia/ 9166
12 (respirat* adj4 (distress* or depress* or fail* or insufficien*)).tw. 90690
13 ARDS.tw. 14418
14 (hypercapni* or hypercabi* or hypox*).tw. 179793
15 (ventilator* adj4 (fail* or depress*)).tw. 2212
16 or/9-15 289144
17 Lung Transplantation/ 17477
18 (lung adj4 (transplant* or graft*)).tw. 20166
19 Pulmonary Disease, Chronic Obstructive/ 49096
20 (Chronic adj4 Obstruct* adj4 (Lung or pulmonary or airway*) adj4 Disease*).tw. 55470
21 ((Chronic adj4 Airflow adj4 Obstruct*) or (COAD or COPD)).tw. 49360
22 or/17-21 100401
23 16 or 22 380563
24 8 and 23 1602
25 (cardiohelp* or novalung* or "iLA activve" or hemolung* or PRISMAlung* or minilung* or prolung* or diapact* or DECAPsmart or CO2RESET or ApherCap or ALung).tw. 202
26 24 or 25 1736
27 animals/ not humans/ 5060478
28 26 not 27 1414
29 limit 28 to english language 1144
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