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NICE real-world evidence framework

  • Corporate document
  • Reference number: ECD9
  • Published:  23 June 2022
  • Corporate document
  • Tools and resources
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  • Overview
  • Introduction to real-world evidence in NICE decision making
  • Conduct of quantitative real-world evidence studies
  • Assessing data suitability
  • Methods for real-world studies of comparative effects
  • Appendix 1: Data Suitability Assessment Tool (DataSAT)
  • Appendix 2: Reporting on methods used to minimise risk of bias
  • Appendix 3: Reporting information for selected analytical methods
  • Appendix 4: Conduct of qualitative research studies
  • How the framework was developed
  • Update information

Overview

This document describes a real-world evidence framework that aims to improve the quality of real-world evidence informing our guidance. The framework does not set minimum standards for the acceptability of evidence. The framework is mainly targeted at those developing evidence to inform NICE guidance. It is also relevant to patients, those collecting data, and reviewers of evidence.

Last reviewed: 23 June 2022


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