Blood transfusion

  • NICE guideline
  • NG24
  • Published: 
  • Last updated: 
Download guidance (PDF)

Update information

February 2026: We have reviewed the evidence and made new recommendations on using tranexamic acid during surgery.

Minor changes since publication

March 2025: In the section on prothrombin complex concentrate we removed the link to NICE's technology appraisal guidance on andexanet alfa (TA697) because the guidance has been updated and no longer applies to this guideline.

August 2023: We added links to the MHRA safety advice on direct-acting oral anticoagulants (DOACs) and NICE's technology appraisal guidance on andexanet alfa for reversing anticoagulation from apixaban or rivaroxaban (TA697) to the section on prothrombin complex concentrate.

March 2022: A link to MHRA advice on intravenous iron was removed.

July 2020: A link to MHRA advice on intravenous iron was added. A link to NICE's guideline on joint replacement (primary) was added to give advice on tranexamic acid in primary hip, knee and shoulder replacement.

ISBN: 978-1-4731-9314-7