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Advanced breast cancer: diagnosis and treatment

  • Clinical guideline
  • Reference number: CG81
  • Published:  23 February 2009
  • Last updated:  30 June 2026
  • Guidance
  • Tools and resources
  • Information for the public
  • Evidence
  • History
Download guidance (PDF)
  • Overview
  • Using this guideline
  • Providing information and supportive care, and data collection to improve care
  • Diagnosis and assessment
  • Systemic anticancer therapy
  • Managing treatment side effects and menopausal symptoms
  • Managing uncontrolled local disease and metastases
  • Terms used in this guideline
  • Recommendations for research
  • Finding more information and committee details
  • Update information

Finding more information and committee details

To find NICE guidance on related topics, including guidance in development, see the NICE topic page on breast cancer.

For full details of the evidence and the guideline committee's discussions, see the evidence reviews and full guideline. You can also find information about how the guideline was developed, including details of the committee.

NICE has produced tools and resources to help you put this guideline into practice. For general help and advice on putting our guidelines into practice, see resources to help you put NICE guidance into practice.


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