Polyendocrine Metabolic Ovarian Syndrome (PMOS)

You can now review and comment on this draft guideline.

The consultation closes on Tuesday 11^th August 2026 at 5pm.

How to comment

1. Register your organisation or comment as an individual

If you’re commenting for an organisation, your organisation needs to be registered as a stakeholder.

Not eligible? Contact the Stakeholder organisation that most closely represents your interests and pass your comments to them.

We can accept comments from individuals. These will be considered, but you won’t get a formal response and they won’t be posted on the NICE website. Wherever possible we encourage you to submit your comments through a registered stakeholder organisation.

This draft guideline is an adaptation of the 2023 international guideline (IG) on PCOS.

The committee reviewed the evidence and recommendations from the IG and assessed their relevance and applicability to the UK context, including current clinical practice and service delivery. Where appropriate, the committee has adapted recommendations to reflect UK‑specific considerations. Original health economic evaluation has also been undertaken to support decision‑making for this guideline.

Where a draft NICE recommendation has been derived from one or more IG recommendations the relevant IG recommendation numbers have been given in brackets at the end of the NICE recommendation. NICE’s assessments of the IG evidence reviews and recommendations, and rationales for the draft NICE recommendations are available in 5 adaptation reports. These correspond to the 5 main sections of the IG and follow the order of the IG’s subsections.

2. Read the consultation documents

Documents to comment on:

• Draft guideline
• Adaptation report 1
• Adaptation report 2
• Adaptation report 3
• Adaptation report 4
• Adaptation report 5
• Methods document
• Supplement A - TVUS AMH model write-up
• Supplement B - Laser HE model write up
• Equality and health inequalities assessment
• Acknowledgements document

If you want to review the economic models, please see 5. Economic models below and fill in the confidentiality form

Other information about the consultation

• Committee member list
• Register of interests
• Developing NICE guidelines: how to get involved
• Final scope – for information

3. Add your comments

• You must use this form.
• You must declare any links with, or funding from, the tobacco industry. 

If you share similar views with another organisation, send a joint response.

Make sure you consider:

• The areas that will have the biggest impact on practice and be challenging to implement.
• How to help users overcome challenges.
• Developing NICE guidelines: how to get involved suggests some other areas to comment on.

4. Email the form to us

Email: PCOS@nice.org.uk

Deadline: Tuesday 11th August 2026  at 5pm

5. Economic model

The developer has produced 2 economic models to support the guideline on;

• AMH versus TVUS for the diagnosis of PCOM
• Laser hair reduction for hirsutism

To receive an executable version of this model, please submit a request to PCOS@nice.org.uk with a signed copy of the confidentiality acknowledgement and undertaking form.

We will then send you a link to an executable version of the economic model by email. The deadline for returning your comments is the same as for the guideline consultation: Tuesday 11th August 2026 at 5pm.