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CG151 Neutropenic sepsis: prophylaxis podcast with Dr Bob Phillips

Dr Bob Phillips, Consultant in Paediatric and Teenage and Young Adult Oncology discusses the evidence behind the clinical guideline recommendations in relation to prophylaxis against neutropenic sepsis.

This podcast is 14.5 minutes in length and specifically applies to the following recommendations:-

  • For adult patients (aged 18 years and older) with acute leukaemias, stem cell transplants or solid tumours in whom significant neutropenia (neutrophil count equal to or lower than 0.5 x 109/litre) is an anticipated consequence of chemotherapy, offer prophylaxis with a fluoroquinolone during the expected period of neutropenia only (1.2.1.1)
  • Monitor rates of antibiotic resistance and infection patterns in patients within treatment facilities where patients are receiving fluoroquinolones for antibiotic prophylaxis of neutropenic sepsis[1] (1.2.1.2)
  • Do not routinely offer G-CSF for the prevention of neutropenic sepsis in adults receiving chemotherapy unless they are receiving G-CSF as an integral part of the chemotherapy regimen or in order to maintain dose intensity (1.2.1.3)

[1] Clostridium difficile infection: How to deal with the problem

Updated guidance on the diagnosis and reporting of Clostridium Difficile



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This podcast was added on 19 Sep 2012

Podcast transcript

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Disclaimer

This resource should be used alongside the published guidance. The information does not supersede or replace the guidance itself.

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This page was last updated: 19 September 2012

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Accessibility | Cymraeg | Freedom of information | Vision Impaired | Contact Us | Glossary | Data protection | Copyright | Disclaimer | Terms and conditions

Copyright 2014 National Institute for Health and Care Excellence. All rights reserved.