In development: Guidance, quality standards and advice

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Guidance, NICE advice and quality standards in development
Title	Type	Expected publication date
Nogapendekin alfa inbakicept with intravesical BCG for non-muscle-invasive bladder cancer with carcinoma in situ that is unresponsive to BCG [ID6582]	Technology appraisal guidance	4 November 2026
Non-invasive skin closure devices for surgical incisions (MT775)	Medical technologies guidance	TBC
Norucholic acid for treating primary sclerosing cholangitis [ID6583]	Technology appraisal guidance	TBC
Nusinersen and risdiplam for treating spinal muscular atrophy (review of TA588 and TA755) [ID6195]	Technology appraisal guidance	TBC
NY-ESO-1 T-cells for treating synovial sarcoma [ID1286]	Technology appraisal guidance	TBC
Obeticholic acid for treating liver fibrosis in people with steatohepatitis [ID1645]	Technology appraisal guidance	TBC
Obicetrapib and obicetrapib–ezetimibe for treating primary hypercholesterolaemia or mixed dyslipidaemia [ID6519]	Technology appraisal guidance	14 October 2026
Obinutuzumab for treating serologically active extra-renal lupus [ID6670]	Technology appraisal guidance	TBC
Obsessive-compulsive disorder and body dysmorphic disorder	Quality standard	16 February 2027
Obsessive-compulsive disorder and body dysmorphic disorder: assessment and management	NICE guideline	16 February 2027
Odevixibat for treating cholestasis and pruritus in Alagille Syndrome [ID6181]	Technology appraisal guidance	TBC
Olezarsen for treating familial chylomicronaemia syndrome [ID6585]	Technology appraisal guidance	19 August 2026
Omburtamab for treating relapsed neuroblastoma [ID1664]	Technology appraisal guidance	TBC
Opicapone for adjunctive treatment of motor signs and symptoms in Parkinson's disease [TSID11941]	Technology appraisal guidance	TBC
Optical Coherence Tomography to guide percutaneous coronary intervention	Interventional procedures guidance	TBC
Oral paclitaxel with encequidar for treating advanced breast cancer [ID5111]	Technology appraisal guidance	TBC
Orforglipron for managing overweight and obesity [ID6516]	Technology appraisal guidance	18 November 2026
Orthopaedic Guidelines on Management of Duchenne Muscular Dystrophy: DMD Care UK standard of care guideline	NICE review	1 April 2026
Osimertinib for maintenance treatment of EGFR mutation-positive locally advanced unresectable non-small-cell lung cancer after platinum-based chemoradiation [ID6223]	Technology appraisal guidance	29 April 2026
Osimertinib for neoadjuvant treatment of EGFR mutation-positive resectable non-small-cell lung cancer [ID6472]	Technology appraisal guidance	TBC
Osteoporosis	Quality standard	TBC
Osteoporosis: risk assessment, treatment, and fragility fracture prevention (update)	NICE guideline	15 July 2026
Oxybutynin hydrochloride for managing neurogenic detrusor overactivity in people 6 years and over with spinal cord injury or spina bifida [ID5089]	Technology appraisal guidance	TBC
Palbociclib with trastuzumab and endocrine therapy for maintenance treatment of hormone-receptor positive, HER2-positive metastatic breast cancer [ID6251]	Technology appraisal guidance	TBC
Palforzia for treating peanut allergy in children aged 1 to 3 [ID6144]	Technology appraisal guidance	TBC

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