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Published guidance, NICE advice and quality standards
Title	Reference number	Published	Last updated
Implantable cardioverter defibrillators and cardiac resynchronisation therapy for arrhythmias and heart failure	TA314	25 June 2014	25 June 2014
Canagliflozin in combination therapy for treating type 2 diabetes	TA315	25 June 2014	25 June 2014
Teriflunomide for treating relapsing–remitting multiple sclerosis	TA303	22 January 2014	1 June 2014
Afatinib for treating epidermal growth factor receptor mutation-positive locally advanced or metastatic non-small-cell lung cancer	TA310	23 April 2014	23 April 2014
Bortezomib for induction therapy in multiple myeloma before high-dose chemotherapy and autologous stem cell transplantation	TA311	23 April 2014	23 April 2014
Rituximab in combination with glucocorticoids for treating anti-neutrophil cytoplasmic antibody-associated vasculitis	TA308	26 March 2014	26 March 2014
Aflibercept in combination with irinotecan and fluorouracil-based therapy for treating metastatic colorectal cancer that has progressed following prior oxaliplatin-based chemotherapy	TA307	25 March 2014	25 March 2014
Total hip replacement and resurfacing arthroplasty for end-stage arthritis of the hip	TA304	26 February 2014	26 February 2014
Aflibercept for treating visual impairment caused by macular oedema secondary to central retinal vein occlusion	TA305	26 February 2014	26 February 2014
Pixantrone monotherapy for treating multiply relapsed or refractory aggressive non-Hodgkin's B‑cell lymphoma	TA306	26 February 2014	26 February 2014
Peginterferon alfa and ribavirin for the treatment of mild chronic hepatitis C	TA106	23 August 2006	27 November 2013
Peginterferon alfa and ribavirin for treating chronic hepatitis C in children and young people	TA300	27 November 2013	27 November 2013
Canakinumab for treating systemic juvenile idiopathic arthritis (terminated appraisal)	TA302	27 November 2013	27 November 2013
Interferon alfa (pegylated and non-pegylated) and ribavirin for the treatment of chronic hepatitis C	TA75	28 January 2004	27 November 2013
Pazopanib for the first-line treatment of advanced renal cell carcinoma	TA215	23 February 2011	1 August 2013
Aripiprazole for treating moderate to severe manic episodes in adolescents with bipolar I disorder	TA292	24 July 2013	24 July 2013
Aflibercept solution for injection for treating wet age‑related macular degeneration	TA294	24 July 2013	24 July 2013
Rivaroxaban for treating pulmonary embolism and preventing recurrent venous thromboembolism	TA287	26 June 2013	26 June 2013
Mirabegron for treating symptoms of overactive bladder	TA290	26 June 2013	26 June 2013
Bevacizumab in combination with paclitaxel and carboplatin for first-line treatment of advanced ovarian cancer	TA284	22 May 2013	22 May 2013
Bevacizumab in combination with gemcitabine and carboplatin for treating the first recurrence of platinum-sensitive advanced ovarian cancer	TA285	22 May 2013	22 May 2013
Loxapine inhalation for treating acute agitation and disturbed behaviours associated with schizophrenia and bipolar disorder (terminated appraisal)	TA286	22 May 2013	22 May 2013
Omalizumab for treating severe persistent allergic asthma	TA278	24 April 2013	24 April 2013
Percutaneous vertebroplasty and percutaneous balloon kyphoplasty for treating osteoporotic vertebral compression fractures	TA279	24 April 2013	24 April 2013
Colistimethate sodium and tobramycin dry powders for inhalation for treating pseudomonas lung infection in cystic fibrosis	TA276	27 March 2013	27 March 2013
Methylnaltrexone for treating opioid-induced bowel dysfunction in people with advanced illness receiving palliative care (terminated appraisal)	TA277	27 March 2013	27 March 2013
Tadalafil for the treatment of symptoms associated with benign prostatic hyperplasia (terminated appraisal)	TA273	23 January 2013	23 January 2013
Vinflunine for the treatment of advanced or metastatic transitional cell carcinoma of the urothelial tract	TA272	23 January 2013	23 January 2013
Ipilimumab for previously treated advanced (unresectable or metastatic) melanoma	TA268	12 December 2012	12 December 2012
Decitabine for the treatment of acute myeloid leukaemia (terminated appraisal)	TA270	12 December 2012	12 December 2012
Dronedarone for the treatment of non-permanent atrial fibrillation	TA197	25 August 2010	1 December 2012
Mannitol dry powder for inhalation for treating cystic fibrosis	TA266	28 November 2012	28 November 2012
Ivabradine for treating chronic heart failure	TA267	28 November 2012	28 November 2012
Denosumab for the prevention of skeletal-related events in adults with bone metastases from solid tumours	TA265	24 October 2012	24 October 2012
Alteplase for treating acute ischaemic stroke	TA264	26 September 2012	26 September 2012
Bevacizumab in combination with capecitabine for the first-line treatment of metastatic breast cancer	TA263	22 August 2012	22 August 2012
Rivaroxaban for the treatment of deep vein thrombosis and prevention of recurrent deep vein thrombosis and pulmonary embolism	TA261	25 July 2012	25 July 2012
Lapatinib or trastuzumab in combination with an aromatase inhibitor for the first-line treatment of metastatic hormone receptor-positive breast cancer that overexpresses HER2	TA257	27 June 2012	27 June 2012
Erlotinib for the first-line treatment of locally advanced or metastatic EGFR-TK mutation-positive non-small-cell lung cancer	TA258	27 June 2012	27 June 2012
Botulinum toxin type A for the prevention of headaches in adults with chronic migraine	TA260	27 June 2012	27 June 2012
Fingolimod for the treatment of highly active relapsing–remitting multiple sclerosis	TA254	25 April 2012	25 April 2012
Tocilizumab for the treatment of rheumatoid arthritis	TA247	22 February 2012	22 February 2012
Rituximab for the first-line treatment of stage III-IV follicular lymphoma	TA243	25 January 2012	25 January 2012
Apixaban for preventing venous thromboembolism after hip or knee replacement surgery	TA245	25 January 2012	25 January 2012
Cetuximab, bevacizumab and panitumumab for the treatment of metastatic colorectal cancer after first-line chemotherapy	TA242	25 January 2012	25 January 2012
Tocilizumab for the treatment of systemic juvenile idiopathic arthritis	TA238	14 December 2011	14 December 2011
Fulvestrant for the treatment of locally advanced or metastatic breast cancer	TA239	14 December 2011	14 December 2011
Mifamurtide for the treatment of osteosarcoma	TA235	26 October 2011	26 October 2011
Ticagrelor for the treatment of acute coronary syndromes	TA236	26 October 2011	26 October 2011
Agomelatine for the treatment of major depressive episodes (terminated appraisal)	TA231	27 July 2011	27 July 2011

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