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This guidance has been updated and replaced by NICE guideline CG160.
This guidance has been updated and replaced by NICE guideline CG172.
Type 2 diabetes foot problems: Prevention and management of foot problems (CG10)
This guidance has been updated and replaced by NICE guideline NG19.
This guidance has been updated and replaced by NICE guideline CG82.
This guidance has been updated and replaced by NICE technology appraisal guidance 156.
Collagenase clostridium histolyticum for treating Dupuytren's contracture (TA459)
We have withdrawn the guidance because collagenase clostridium histolyticum (Xiapex) is no longer available in the UK.
The clinical effectiveness and cost effectiveness of surgery for people with morbid obesity (TA46)
This guidance has been updated and replaced by NICE guideline CG43.
Olaratumab in combination with doxorubicin for treating advanced soft tissue sarcoma (TA465)
This guidance has been withdrawn because olaratumumab (Lartruvo) no longer has a marketing authorisation.
This advice has been withdrawn because Novartis has discontinued ofatumumab (Arzerra). Ofatumumab will continue to be available for people who need it. Contact Clinigen at managedacess@clinigengroup.com or 01932 842100 for details.
Eluxadoline for treating irritable bowel syndrome with diarrhoea (TA471)
We have withdrawn this guidance. Allergan has stopped marketing eluxadoline (Truberzi) for commercial reasons and its marketing authorisation has been withdrawn.
Obinutuzumab with bendamustine for treating follicular lymphoma refractory to rituximab (TA472)
This guidance has been updated and replaced by NICE technology appraisal guidance 629.
Belimumab for treating active autoantibody-positive systemic lupus erythematosus (TA397)
This guidance has been updated and replaced by NICE technology appraisal guidance 752.
Lumacaftor–ivacaftor for treating cystic fibrosis homozygous for the F508del mutation (TA398)
This guidance has been updated and replaced by NICE technology appraisal guidance 988.
This guidance has been replaced by NICE technology appraisal guidance 71.
The clinical effectiveness and cost effectiveness of infliximab for Crohn's disease (TA40)
This guidance has been updated and replaced by NICE technology appraisal guidance 187.
Guidance on the use of metal on metal hip resurfacing arthroplasty (TA44)
This guidance has been updated and replaced by NICE technology appraisal guidance 304.
Daclizumab for treating relapsing–remitting multiple sclerosis (TA441)
This guidance has been withdrawn because Biogen is withdrawing its marketing authorisations for daclizumab. See the European Medicines Agency’s advice on daclizumab.
Brentuximab vedotin for treating CD30-positive Hodgkin lymphoma (TA446)
This guidance has been updated and replaced by NICE technology appraisal guidance 524.
Pembrolizumab for untreated PD-L1-positive metastatic non-small-cell lung cancer (TA447)
This guidance has been updated and replaced by NICE technology appraisal guidance 531.
This guidance has been updated and replaced by NICE guideline NG107
Nivolumab for previously treated squamous non-small-cell lung cancer (TA483)
This technology appraisal guidance has been updated and replaced by NICE technology appraisal guidance 655.
Nivolumab for previously treated non-squamous non-small-cell lung cancer (TA484)
This guidance has been updated and replaced by NICE technology appraisal guidance 713.
Venetoclax for treating chronic lymphocytic leukaemia (TA487)
This guidance has been updated and replaced by NICE technology appraisal guidance 796.
This guidance has been updated and replaced by NICE technology appraisal guidance 653.
Human growth hormone for the treatment growth failure in children (TA42)
This guidance has been updated and replaced by NICE technology appraisal guidance 188.
This guidance has been updated and replaced by NICE guideline CG82.
Mepolizumab for treating severe refractory eosinophilic asthma (TA431)
This technology appraisal guidance has been updated and replaced by NICE technology appraisal guidance 671.
This guidance has been updated and replaced by NICE technology appraisal guidance 91.
This guidance has been updated and replaced by NICE technology appraisal guidance 427.
This technology appraisal guidance has been updated and replaced by NICE technology appraisal guidance 657
This guidance has been updated and replaced by NICE technology appraisal guidance 736.
Ibrutinib for treating Waldenstrom's macroglobulinaemia (TA491)
This guidance has been updated and replaced by NICE technology appraisal guidance 795.
This guidance has been updated and replaced by NICE technology appraisal guidance 739.
Cladribine tablets for treating relapsing–remitting multiple sclerosis (TA493)
This guidance has been updated and replaced by NICE technology appraisal guidance 616.
This guidance has been updated and replaced by NICE guideline CG40. [Replaced by NICE guideline CG171 (September 2013)]
This guidance has been updated and replaced by NICE technology appraisal guidance 898.
This guidance has been updated and replaced by NICE technology appraisal guidance 933. People already having tisagenlecleucel for relapsed or refractory diffuse large B-cell lymphoma after 2 or more systemic therapies through the Cancer Drugs Fund can continue. For those people, it will be funded by the company until they and their NHS clinician consider it appropriate to stop.
The clinical effectiveness and cost effectiveness of insulin pump therapy (TA57)
This appraisal has been updated and replaced by NICE technology appraisal guidance 151.
Daratumumab with bortezomib and dexamethasone for previously treated multiple myeloma (TA573)
This guidance has been updated and replaced by NICE technology appraisal guidance 897.
This guidance has been updated and replaced by NICE technology appraisal guidance 870.
Lesinurad for treating chronic hyperuricaemia in people with gout (TA506)
We have withdrawn this guidance. Grünenthal has stopped marketing Lesinurad (Zurampic) for commercial reasons and its marketing authorisation has been withdrawn.
Computerised cognitive behaviour therapy (CCBT) for the treatment of depression and anxiety (TA51)
This guidance has been updated and replaced by NICE technology appraisal guidance 97.
Daratumumab monotherapy for treating relapsed and refractory multiple myeloma (TA510)
This guidance has been updated and replaced by NICE technology appraisal guidance 783.
Regorafenib for previously treated advanced hepatocellular carcinoma (TA514)
This guidance has been updated and replaced by NICE technology appraisal guidance 555.
This guidance has been replaced by NICE technology appraisal guidance 69.
This guidance has been updated and replaced by NICE technology appraisal guidance 70 [Partially updated by NICE technology appraisal guidance 241].
This guidance has been updated and replaced by NICE technology appraisal guidance TA798.
Flu treatment - zanamivir, amantadine and oseltamivir (TA58)
This guidance has been updated and replaced by NICE technology appraisal guidance 168.
Nivolumab with ipilimumab for untreated advanced renal cell carcinoma (TA581)
This guidance has been updated and replaced by NICE technology appraisal guidance 780.