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This guidance has been updated and replaced by NICE guideline NG28.
Eribulin for the treatment of locally advanced or metastatic breast cancer (TA250)
This guidance has been updated and replaced by NICE technology appraisal guidance 423 and NICE technology appraisal guidance 515.
This guidance has been updated and replaced by NICE technology appraisal guidance 426.
Ranibizumab for the treatment of diabetic macular oedema (TA237)
This guidance has been updated and replaced by NICE technology appraisal guidance 274.
This guidance has been replaced by NICE guideline CG74.
Telaprevir for the treatment of genotype 1 chronic hepatitis C (TA252)
Telaprevir no longer has a marketing authorisation in the UK so this guidance has been withdrawn.
Boceprevir for the treatment of genotype 1 chronic hepatitis C (TA253)
Boceprevir is no longer available in the UK so this guidance has been withdrawn.
This guidance has been updated and replaced by NICE technology appraisal guidance 391.
This guidance has been replaced by NICE guideline CG24 [Replaced by NICE guideline CG121].
Adalimumab for the treatment of moderate to severe ulcerative colitis (terminated appraisal) (TA262)
This guidance has been updated and replaced by NICE technology appraisal guidance 329.
This guidance has been withdrawn because Novartis has discontinued ofatumumab (Arzerra). Ofatumumab will continue to be available for people who need it. Contact Clinigen at managedacess@clinigengroup.com or 01932 842100 for details.
Liraglutide for the treatment of type 2 diabetes mellitus (TA203)
This guidance has been updated and replaced by NICE guideline NG28.
Eltrombopag for the treatment of chronic immune (idiopathic) thrombocytopenic purpura (TA205)
This guidance has been updated and replaced by NICE technology appraisal guidance 293.
This guidance has been replaced by NICE technology appraisal guidance 63 [Replaced by NICE guideline CG66].
Imatinib for the adjuvant treatment of gastrointestinal stromal tumours (TA196)
This guidance has been replaced by NICE technology appraisal guidance 326.
Tocilizumab for the treatment of rheumatoid arthritis (TA198)
This guidance has been updated and replaced by NICE technology appraisal guidance 247.
Guidance on the Selection of Prostheses for Primary Total Hip Replacement (TA2)
This guidance has been updated and replaced by NICE technology appraisal guidance 304.
Omalizumab for the treatment of severe persistent allergic asthma in children aged 6–11 (TA201)
This guidance has been updated and replaced by NICE technology appraisal guidance 278.
Everolimus for the second-line treatment of advanced renal cell carcinoma (TA219)
This guidance has been updated and replaced by NICE technology appraisal guidance 432.
This guidance has been replaced by NICE guideline CG43.
Trabectedin for the treatment of relapsed ovarian cancer (TA222)
This guidance has been updated and replaced by NICE technology appraisal guidance 389.
This guidance has been updated and replaced by NICE technology appraisal guidance 375.
This guidance has been updated and replaced by NICE technology appraisal guidance 156.
This guidance has been updated and replaced by NICE technology appraisal guidance 736.
Ibrutinib for treating Waldenstrom's macroglobulinaemia (TA491)
This guidance has been updated and replaced by NICE technology appraisal guidance 795.
This guidance has been updated and replaced by NICE technology appraisal guidance 739.
Cladribine tablets for treating relapsing–remitting multiple sclerosis (TA493)
This guidance has been updated and replaced by NICE technology appraisal guidance 616.
This guidance has been replaced by NICE technology appraisal guidance 69.
This guidance has been updated and replaced by NICE technology appraisal guidance 70 [Partially updated by NICE technology appraisal guidance 241].
This technology appraisal guidance has been updated and replaced by NICE technology appraisal guidance 657
Collagenase clostridium histolyticum for treating Dupuytren's contracture (TA459)
We have withdrawn the guidance because collagenase clostridium histolyticum (Xiapex) is no longer available in the UK.
The clinical effectiveness and cost effectiveness of surgery for people with morbid obesity (TA46)
This guidance has been updated and replaced by NICE guideline CG43.
Olaratumab in combination with doxorubicin for treating advanced soft tissue sarcoma (TA465)
This guidance has been withdrawn because olaratumumab (Lartruvo) no longer has a marketing authorisation.
Belimumab for treating active autoantibody-positive systemic lupus erythematosus (TA397)
This guidance has been updated and replaced by NICE technology appraisal guidance 752.
Lumacaftor–ivacaftor for treating cystic fibrosis homozygous for the F508del mutation (TA398)
This guidance has been updated and replaced by NICE technology appraisal guidance 988.
This guidance has been replaced by NICE technology appraisal guidance 71.
The clinical effectiveness and cost effectiveness of infliximab for Crohn's disease (TA40)
This guidance has been updated and replaced by NICE technology appraisal guidance 187.
Guidance on the use of metal on metal hip resurfacing arthroplasty (TA44)
This guidance has been updated and replaced by NICE technology appraisal guidance 304.
Daclizumab for treating relapsing–remitting multiple sclerosis (TA441)
This guidance has been withdrawn because Biogen is withdrawing its marketing authorisations for daclizumab. See the European Medicines Agency’s advice on daclizumab.
Brentuximab vedotin for treating CD30-positive Hodgkin lymphoma (TA446)
This guidance has been updated and replaced by NICE technology appraisal guidance 524.
Pembrolizumab for untreated PD-L1-positive metastatic non-small-cell lung cancer (TA447)
This guidance has been updated and replaced by NICE technology appraisal guidance 531.
This guidance has been updated and replaced by NICE technology appraisal guidance 91.
This advice has been withdrawn because Novartis has discontinued ofatumumab (Arzerra). Ofatumumab will continue to be available for people who need it. Contact Clinigen at managedacess@clinigengroup.com or 01932 842100 for details.
Eluxadoline for treating irritable bowel syndrome with diarrhoea (TA471)
We have withdrawn this guidance. Allergan has stopped marketing eluxadoline (Truberzi) for commercial reasons and its marketing authorisation has been withdrawn.
Obinutuzumab with bendamustine for treating follicular lymphoma refractory to rituximab (TA472)
This guidance has been updated and replaced by NICE technology appraisal guidance 629.
This guidance has been updated and replaced by NICE guideline NG107
Nivolumab for previously treated squamous non-small-cell lung cancer (TA483)
This technology appraisal guidance has been updated and replaced by NICE technology appraisal guidance 655.
Nivolumab for previously treated non-squamous non-small-cell lung cancer (TA484)
This guidance has been updated and replaced by NICE technology appraisal guidance 713.
Venetoclax for treating chronic lymphocytic leukaemia (TA487)
This guidance has been updated and replaced by NICE technology appraisal guidance 796.
This guidance has been updated and replaced by NICE technology appraisal guidance 653.