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This guidance has been updated and replaced by NICE technology appraisal guidance TA798.
Flu treatment - zanamivir, amantadine and oseltamivir (TA58)
This guidance has been updated and replaced by NICE technology appraisal guidance 168.
Nivolumab with ipilimumab for untreated advanced renal cell carcinoma (TA581)
This guidance has been updated and replaced by NICE technology appraisal guidance 780.
Cabozantinib for previously treated advanced hepatocellular carcinoma (terminated appraisal) (TA582)
This guidance has been updated and replaced by NICE technology appraisal guidance 849.
Cemiplimab for treating metastatic or locally advanced cutaneous squamous cell carcinoma (TA592)
This guidance has been updated and replaced by NICE technology appraisal guidance TA802.
This guidance has been updated and replaced by NICE technology appraisal guidance 687.
Brentuximab vedotin for untreated advanced Hodgkin lymphoma (terminated appraisal) (TA594)
This guidance has been updated and replaced by NICE technology appraisal guidance 1059.
Dapagliflozin with insulin for treating type 1 diabetes (TA597)
In November 2021, we withdrew this guidance because dapagliflozin (Forxiga) with insulin is no longer licensed for treating type 1 diabetes.
This guidance has been replaced by NICE technology appraisal guidance 30 [Replaced by NICE guideline CG81].
Guidance on the use of patient-education models for diabetes (TA60)
This guidance has been replaced by NICE guideline NG17.
This guidance has been updated and replaced by NICE technology appraisal guidance 770.
Bezlotoxumab for preventing recurrent Clostridium difficile infection (terminated appraisal) (TA601)
This guidance has been updated and replaced by NICE guideline NG199.
This guidance has been updated and replaced by NICE technology appraisal guidance 692.
This technology appraisal guidance has been updated and replaced by NICE technology appraisal guidance 674. People already taking pembrolizumab for untreated PD-L1-positive locally advanced or metastatic urothelial cancer when cisplatin is unsuitable through the Cancer Drugs Fund can continue. For those people, it will be funded by the company until they and their doctor decide when best to stop.
This guidance has been updated and replaced by NICE technology appraisal guidance 784.
Crizotinib for treating ROS1-positive advanced non-small-cell lung cancer (TA529)
This guidance has been updated and replaced by NICE technology appraisal guidance 1021.
This guidance has been updated and replaced by NICE guideline CG40. [Replaced by NICE guideline CG171 (September 2013)]
This guidance has been updated and replaced by NICE technology appraisal guidance 898.
This guidance has been updated and replaced by NICE technology appraisal guidance 933. People already having tisagenlecleucel for relapsed or refractory diffuse large B-cell lymphoma after 2 or more systemic therapies through the Cancer Drugs Fund can continue. For those people, it will be funded by the company until they and their NHS clinician consider it appropriate to stop.
Pembrolizumab for adjuvant treatment of resected melanoma with high risk of recurrence (TA553)
This guidance has been updated and replaced by NICE technology appraisal guidance 766.
This guidance has been updated and replaced by NICE technology appraisal guidance 975.
This guidance has been updated and replaced by NICE technology appraisal guidance 683.
This guidance has been updated and replaced by NICE technology appraisal guidance 684.
We have withdrawn the guidance because cenegermin (Oxervate) is no longer available in the UK.
Guidance on the use of vinorelbine for the treatment of advanced breast cancer (TA54)
This guidance has been updated and replaced by NICE guideline CG81.
This guidance has been updated and replaced by NICE technology appraisal guidance 870.
This guidance has been updated and replaced by NICE technology appraisal guidance 836.
This appraisal has been updated and replaced by NICE guideline CG81.
This guidance has been updated and replaced by NICE technology appraisal guidance 908.
Osimertinib for untreated EGFR mutation-positive non-small-cell lung cancer (TA621)
This technology appraisal guidance has been updated and replaced by NICE technology appraisal guidance 654
Sotagliflozin with insulin for treating type 1 diabetes (TA622)
NICE has withdrawn this guidance. This is because the company is no longer marketing sotagliflozin (Zynquista) and its marketing authorisation has been withdrawn.
This guidance has been updated and replaced by NICE guideline CG66 [partially updated by NICE guideline CG87]).
Entrectinib for treating NTRK fusion-positive solid tumours (TA644)
This guidance has been updated and replaced by NICE technology appraisal guidance 1118. People already having entrectinib for treating neurotrophic tyrosine receptor kinase (NTRK) fusion-positive solid tumours through the Cancer Drugs Fund will be able to continue until they and their healthcare professional decide when best to stop.
Avelumab with axitinib for untreated advanced renal cell carcinoma (TA645)
This guidance has been updated and replaced by NICE technology appraisal guidance 1120.
Guidance on the use of photodynamic therapy for age-related macular degeneration (TA68)
This guidance has been updated and replaced by NICE guideline NG82.
This guidance has been updated and replaced by NICE technology appraisal guidance TA1007.
This guidance has been updated and replaced by NICE technology appraisal guidance 764.
Teduglutide for treating short bowel syndrome (terminated appraisal) (TA690)
This guidance has been updated and replaced by NICE technology appraisal guidance TA804.
This guidance has been updated and replaced by NICE technology appraisal guidance 946.
Tafamidis for treating transthyretin amyloidosis with cardiomyopathy (TA696)
This guidance has been updated and replaced by NICE technology appraisal guidance 984.
The clinical and cost effectiveness of proton pump inhibitors for the treatment of dyspepsia (TA7)
This guidance has been replaced by NICE guideline CG17. [Replaced by NICE guideline CG184]
This guidance has been updated and replaced by NICE technology appraisal guidance 970 and NICE technology appraisal guidance 974.
After consultation the guidance has been withdrawn because it is no longer relevant to clinical practice. Rituximab is now routinely used outside its licensed indication. See NICE’s guideline on non-Hodgkin’s lymphoma.
This guidance has been updated and replaced by NICE technology appraisal guidance 816.
The clinical effectiveness and cost effectiveness of new drugs for bipolar disorder (TA66)
This guidance has been updated and replaced NICE guideline CG38.
Venetoclax with obinutuzumab for untreated chronic lymphocytic leukaemia (TA663)
This guidance has been updated and replaced by NICE technology appraisal guidance 1119.