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Showing 5971 to 5985 of 8222 results

  1. Long-term safety of tenofovir disoproxil in chronic hepatitis B:- Further research should be undertaken to determine the long-term safety of tenofovir disoproxil, including the risk of clinically significant hypophosphataemia and related bone toxicity, in people with chronic hepatitis B. The cost effectiveness of routine monitoring for phosphate loss and bone disease in people with chronic hepatitis B who are receiving tenofovir disoproxil treatment needs further evaluation.

    Recommendation ID CG165/3 Question Long-term safety of tenofovir disoproxil in chronic hepatitis B:- Further research should be undertaken

    Research recommendation
    Published
    9 June 2015

  2. Magnesium sulfate for neuroprotection: bolus plus infusion compared with bolus alone:- What is the clinical effectiveness of a bolus plus infusion of magnesium sulfate compared with a bolus alone for preventing neurodevelopmental injury in babies born preterm?

    Recommendation ID NG25/4 Question Magnesium sulfate for neuroprotection: bolus plus infusion compared with bolus alone:- What is the clinical

    Research recommendation
    Published
    11 December 2015

  3. Maintaining benefits after successful treatment of anorexia nervosa:- What factors (including comorbidities, personal, social and demographic factors, treatment type,and subsequent relapse prevention interventions) are associated with continued benefit after successful treatment for anorexia nervosa?

    Recommendation ID NG69/5 Question Maintaining benefits after successful treatment of anorexia nervosa:- What factors (including comorbidities

    Research recommendation
    Published
    12 October 2018

  4. Maintaining the benefits of early intervention in psychosis services after discharge:- How can the benefits of early intervention in psychosis services be maintained once service users are discharged after 3 years?

    Recommendation ID CG178/4 Question Maintaining the benefits of early intervention in psychosis services after discharge:- How can the benefits

    Research recommendation
    Published
    9 June 2015

  5. Maintenance treatment:- In the maintenance treatment of bipolar disorder, what is the relative effect on quality of life of lithium, an antipsychotic (haloperidol, olanzapine, quetiapine or risperidone), or a combination of lithium and an antipsychotic?

    Recommendation ID CG185/2 Question Maintenance treatment:- In the maintenance treatment of bipolar disorder, what is the relative effect

    Research recommendation
    Published
    9 June 2015

  6. What is the best and most cost-effective management strategy for people whose first surgery for primary hyperparathyroidism is not successful?

    Recommendation ID NG132/2 Question What is the best and most cost-effective management strategy for people whose first surgery for primary

    Research recommendation
    Published
    25 October 2019

  7. What is the effectiveness and safety of sacral nerve stimulation and transanal irrigation compared to symptomatic treatment for people with major low anterior resection syndrome?

    Recommendation ID NG151/2 Question What is the effectiveness and safety of sacral nerve stimulation and transanal irrigation compared to

    Research recommendation
    Published
    10 February 2020

  8. For people with different causes of shoulder pain after stroke, what is the clinical and cost effectiveness of interventions in reducing pain?

    Recommendation ID NG236/5 Question For people with different causes of shoulder pain after stroke, what is the clinical and cost effectiveness

    Research recommendation
    Published
    11 January 2024

  9. Management of smouldering myeloma:- Which combinations of FISH, molecular technologies, bone marrow plasma cell percentage, whole-body imaging, immunophenotype, serum-free light-chain levels or ratio, Hevylite, paraprotein levels, immunoparesis, and International Staging System (ISS) are most effective at risk stratification for people with smouldering myeloma? What is the comparative effectiveness of fixed duration treatment (with or without bone-directed therapy), continuous treatment (with or without bone-directed therapy) and no treatment (with or without bone-directed therapy) for people with smouldering myeloma?

    Recommendation ID NG35/3 Question Management of smouldering myeloma:- Which combinations of FISH, molecular technologies, bone marrow plasma

    Research recommendation
    Published
    5 April 2016

  10. Management of stable angina in people with evidence of ischaemia on non-invasive functional testing:- Do people with stable angina and evidence of reversible ischaemia on noninvasive functional testing who are on optimal drug treatment benefit from routine coronary angiography with a view to revascularisation?

    Recommendation ID CG126/2 Question Management of stable angina in people with evidence of ischaemia on non-invasive functional testing:-

    Research recommendation
    Published
    9 June 2015

  11. Management strategies to reduce the risk of symptomatic urinary tract infections:- In people with neurogenic lower urinary tract dysfunction, which management strategies (including the use of prophylactic antibiotics and various invasive and non-invasive techniques to aid bladder drainage) reduce the risk of symptomatic urinary tract infections?

    Recommendation ID CG148/3 Question Management strategies to reduce the risk of symptomatic urinary tract infections:- In people with neurogenic

    Research recommendation
    Published
    9 June 2015

  12. What is the most clinical and cost-effective strategy, as identified by a consensus survey, for the perioperative management of anticoagulation treatment in people taking a vitamin K antagonist with a target international normalised ratio (INR) of more than 3 who need bridging therapy?

    Recommendation ID NG180/3 Question What is the most clinical and cost-effective strategy, as identified by a consensus survey, for the

    Research recommendation
    Published
    26 October 2020

  13. Mental health interventions to support discharge from general inpatient hospital settings:- What interventions are cost effective in supporting people with mental health difficulties on discharge from general hospital inpatient settings?

    Recommendation ID NG27/3 Question Mental health interventions to support discharge from general inpatient hospital settings:- What interventions

    Research recommendation
    Published
    29 January 2016

  14. Methods and approaches for gathering the experiences of people who use adult social care services:- When conducting research for the purposes of service improvement, what research methods are acceptable, appropriate and effective in meaningfully gathering the views and experiences of people who use services?

    Recommendation ID NG86/1 Question Methods and approaches for gathering the experiences of people who use adult social care services:- When

    Research recommendation
    Published
    14 November 2018

  15. Methotrexate and risk of hepatotoxicity:- What is the impact of methotrexate compared with other approaches to care (for example other systemic non-biological or biological treatments) on risk of significant liver disease in people with psoriasis and do risk factors such as obesity, alcohol use or diabetes alter this risk?

    Recommendation ID CG153/2 Question Methotrexate and risk of hepatotoxicity:- What is the impact of methotrexate compared with other approaches

    Research recommendation
    Published
    9 June 2015