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Showing 4486 to 4500 of 8213 results

  1. Techniques for confirming a diagnosis in people with suspected atypical Spitzoid melanocytic lesions: In people with reported atypical Spitzoid lesions, how effective are fluorescence in situ hybridization (FISH), comparative genomic hybridization (CGH) and tests to detect driver mutations compared with histopathological examination alone in predicting disease specific survival? This should be investigated ina prospective diagnostic study. Secondary outcomes should include sensitivity, specificity, accuracy, positive predictive value, disease specific survival and progression free survival.

    Recommendation ID NG14/07 Question Techniques for confirming a diagnosis in people with suspected atypical Spitzoid melanocytic lesions:

    Research recommendation
    Published
    4 August 2022

  2. Vitamin D supplementation: In people with stage I to III melanoma does vitamin D supplementation improve overall survival? This should be investigated in a placebo controlled randomised trial. Secondary outcomes should include disease specific survival and toxicity, including the development of renal stones and hypercalcaemia.

    Recommendation ID NG14/09 Question Vitamin D supplementation: In people with stage I to III melanoma does vitamin D supplementation improve

    Research recommendation
    Published
    4 August 2022

  3. In people with suspected COVID-19-associated pulmonary aspergillosis (CAPA), what are the most accurate tests for diagnosing the infection and when should they be done?

    Recommendation ID NG191/12 Question In people with suspected COVID-19-associated pulmonary aspergillosis (CAPA), what are the most accurate

    Research recommendation
    Published
    17 December 2021

  4. Diagnostic criteria: In people with suspected ME/CFS, how effective is the NICE 2021 consensus-based diagnostic criteria in identifying people with ME/CFS?

    Recommendation ID NG206/03 Question Diagnostic criteria: In people with suspected ME/CFS, how effective is the NICE 2021 consensus-based

    Research recommendation
    Published
    8 November 2021

  5. Diagnosis of chronic pancreatitis:- In people with suspected (or under investigation for) chronic pancreatitis, whose diagnosis has not been confirmed by the use of 'first-line' tests (for example, CT scan, ultrasound scan, upper gastrointestinal [GI] endoscopy or combinations of these), what is the accuracy of magnetic resonance cholangiopancreatography (MRCP) with or without secretin and endoscopic ultrasound to identify whether chronic pancreatitis is present?

    Recommendation ID NG104/1 Question Diagnosis of chronic pancreatitis:- In people with suspected (or under investigation for) chronic pancreatitis

    Research recommendation
    Published
    17 December 2018

  6. Is an integrated care system effective at promoting successful progress for people with complex psychosis to a more independent setting?

    Recommendation ID NG181/6 Question Is an integrated care system effective at promoting successful progress for people with complex psychosis

    Research recommendation
    Published
    26 October 2020

  7. Intensity of home care packages:- What is the effectiveness and cost effectiveness of different intensities of home care packages for older people with a range of care and support needs?

    Recommendation ID NG21/1 Question Intensity of home care packages:- What is the effectiveness and cost effectiveness of different intensities

    Research recommendation
    Published
    13 October 2015

  8. What is the clinical and cost effectiveness of more intensive cognitive and psychological therapy compared to usual care for people after a stroke?

    Recommendation ID NG236/2 Question What is the clinical and cost effectiveness of more intensive cognitive and psychological therapy compared

    Research recommendation
    Published
    11 January 2024

  9. What is the clinical and cost effectiveness of delivering rehabilitation for 7 days a week compared to 5 days a week for people after a stroke?

    Recommendation ID NG236/1 Question What is the clinical and cost effectiveness of delivering rehabilitation for 7 days a week compared

    Research recommendation
    Published
    11 January 2024

  10. Does intensive monitoring of people at risk of diabetic foot disease reduce the morbidity associated with developing the disease and is such monitoring cost effective?

    Recommendation ID NG19/1 Question Does intensive monitoring of people at risk of diabetic foot disease reduce the morbidity associated

    Research recommendation
    Published
    15 November 2019

  11. Intensive monitoring for people at risk of diabetic foot problems:- Does intensive monitoring of people at risk of diabetic foot disease reduce the morbidity associated with developing the disease and is such monitoring cost effective?

    Recommendation ID NG19/1 Question Intensive monitoring for people at risk of diabetic foot problems:- Does intensive monitoring of people

    Research recommendation
    Published
    12 October 2015

  12. Further research should be in the form of randomised controlled trials or registries. It should report:

    Recommendation ID IPG778 Question Further research should be in the form of randomised controlled trials or registries. It should report:

    Research recommendation
    Published
    11 January 2024

  13. Intermittent urinary catheters: catheter selection:- For patients performing intermittent self-catheterisation over the long term, what is the clinical and cost effectiveness of single-use non-coated versus single-use hydrophilic versus single-use gel reservoir versus reusable non-coated catheters with regard to the following outcomes: symptomatic urinary tract infections, urinary tract infection-associated bacteraemia, mortality, patient comfort and preference, quality of life, and clinical symptoms of urethral damage?

    Recommendation ID CG139/3 Question Intermittent urinary catheters: catheter selection:- For patients performing intermittent self-catheterisation

    Research recommendation
    Published
    9 June 2015

  14. NICE encourages further research comparing ultrasound-enhanced, catheter-directed thrombolysis for deep vein thrombosis against catheter-directed thrombolysis alone. Patient selection should be documented, including the duration and extent of thrombosis. The dose of thrombolytic agent used and the duration of thrombolysis should be reported, together with all complications. Outcome measures should include the success of thrombolysis (complete, partial or failed) and long-term sequelae. NICE may update the guidance on publication of further evidence.

    Recommendation ID IPG523/1 Question NICE encourages further research comparing ultrasound-enhanced, catheter-directed thrombolysis for

    Research recommendation
    Published
    5 October 2015

  15. NICE encourages further research into arthroscopic trochleoplasty for patellar instability, including publication of consecutive patient series. Patient selection should be described in detail. Reported outcomes should include functional and quality‑of‑life measures, as well as reoperation rates.

    Recommendation ID IPG474/1 Question NICE encourages further research into arthroscopic trochleoplasty for patellar instability, including

    Research recommendation
    Published
    9 June 2015