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Area of interest

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Type

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Status

Last updated

Last updated

Guidance programme

Advice programme

Showing 4576 to 4590 of 8213 results

  1. NICE considered that if enzalutamide is used in routine clinical practice for treating hormone relapsed metastatic prostate cancer that has been previously treated with abiraterone, data should be collected on resource use and overall survival.

    Recommendation ID TA316/2 Question NICE considered that if enzalutamide is used in routine clinical practice for treating hormone relapsed

    Research recommendation
    Published
    9 June 2015

  2. NICE considered that more research is needed to establish the treatment sequence for vemurafenib and ipilimumab in patients who have BRAF V600 mutation-positive melanoma.

    Recommendation ID TA319/1 Question NICE considered that more research is needed to establish the treatment sequence for vemurafenib and

    Research recommendation
    Published
    9 June 2015

  3. NICE considered that there is an important need for head-to-head comparisons between biological treatments for psoriatic arthritis, particularly in people for whom treatment with tumour necrosis factor (TNF) alpha inhibitors has been unsuccessful.

    Recommendation ID TA340/1 Question NICE considered that there is an important need for head-to-head comparisons between biological treatments

    Research recommendation
    Published
    5 October 2015

  4. NICE encourages clinicians to enter patients into research studies with the particular aims of guiding selection of patients and of defining the place of percutaneous balloon cryoablation in relation to other procedures for treating atrial fibrillation. Further research should define patient selection criteria clearly and should document adverse events and long-term control of atrial fibrillation.

    Recommendation ID IPG427/1 Question NICE encourages clinicians to enter patients into research studies with the particular aims of guiding

    Research recommendation
    Published
    9 June 2015

  5. NICE encourages further data collection, including randomised controlled trials on microstructural scaffold insertion without autologous cell implantation for repairing symptomatic chondral knee defects. Studies should clearly describe patient selection, clinical indications and adjunctive treatments. Outcome measures should include symptom relief, functional ability, long-term outcomes measured by appropriate imaging techniques and patient-reported outcomes.

    Recommendation ID IPG560/1 Question NICE encourages further data collection, including randomised controlled trials on microstructural

    Research recommendation
    Published
    9 August 2016

  6. NICE encourages further research and data collection on endoscopic full thickness removal of non-lifting colonic polyps and may update the guidance on publication of further evidence. This should include safety and efficacy outcomes such as perforation, bleeding, the need for immediate re-intervention, inadequate resection and longer-term follow-up of patients found to have malignant disease.

    Recommendation ID IPG580/1 Question NICE encourages further research and data collection on endoscopic full thickness removal of non-lifting

    Research recommendation
    Published
    12 October 2018

  7. NICE encourages further research and data collection on partial replacement of the meniscus of the knee using a biodegradable scaffold. This should include clear descriptions of patient selection and adjunctive treatments. Outcome measures should include symptom relief and functional ability in the short term and the need for further treatment in the longer term.

    Recommendation ID IPG430/1 Question NICE encourages further research and data collection on partial replacement of the meniscus of the

    Research recommendation
    Published
    9 June 2015

  8. NICE encourages further research and publication of results from consecutive case series of patients having this procedure. Details of patient selection should be clearly documented. Reported outcomes should include the effects of the procedure on symptoms and quality of life, the duration of benefits, and the need for further procedures. All complications should be reported. NICE may review this procedure in the light of longer-term outcomes.

    Recommendation ID IPG475/1 Question NICE encourages further research and publication of results from consecutive case series of patients

    Research recommendation
    Published
    9 June 2015

  9. NICE encourages further research and publication on efficacy of miniature lens system implantation for advanced age-related macular degeneration (AMD) which patients may benefit and on safety and efficacy outcomes, particularly longer-term results. NICE may update the guidance on publication of further evidence.

    Recommendation ID IPG565/1 Question NICE encourages further research and publication on efficacy of miniature lens system implantation

    Research recommendation
    Published
    17 October 2016

  10. NICE encourages further research comparing autologous blood injections (with or without techniques to produce platelet-rich plasma) against established nonsurgical methods for managing tendinopathy. Trials should clearly describe patient selection (including the site of tendinopathy, duration of symptoms and any prior treatments) and document whether a 'dry needling' technique is used. Outcomes should include specific measures of pain, quality of life and function, and whether subsequent surgical intervention is needed.

    Recommendation ID IPG438/1 Question NICE encourages further research comparing autologous blood injections (with or without techniques

    Research recommendation
    Published
    9 June 2015

  11. NICE encourages further research into faecal microbiota transplant for C. difficile infection, specifically to investigate optimal dosage, mode of administration and choice of donor.

    Recommendation ID IPG485/1 Question NICE encourages further research into faecal microbiota transplant for C. difficile infection, specifically

    Research recommendation
    Published
    9 June 2015

  12. NICE encourages further research into focal cryoablation for localised prostate cancer. This should take the form of controlled studies comparing the procedure against other forms of management. Studies should clearly define patient selection criteria and should report outcomes including local recurrence in the long term.

    Recommendation ID IPG423/1 Question NICE encourages further research into focal cryoablation for localised prostate cancer. This should

    Research recommendation
    Published
    9 June 2015

  13. NICE encourages further research into the efficacy of MRI-guided transcutaneous focused ultrasound for uterine fibroids. Research studies should report long-term outcomes, including the need for further treatment. Data on the incidence and outcomes of subsequent pregnancy in patients who choose this procedure because they wish to maintain or improve their fertility are particularly important.

    Recommendation ID IPG413/1 Question NICE encourages further research into the efficacy of MRI-guided transcutaneous focused ultrasound

    Research recommendation
    Published
    9 June 2015

  14. NICE encourages further research into the role of negative pressure wound therapy (NPWT) for the open abdomen. Patient selection should be documented and research should report on efficacy outcomes such as impact on wound care and healing rates, and duration of hospital stay.

    Recommendation ID IPG467/1 Question NICE encourages further research into the role of negative pressure wound therapy (NPWT) for the open

    Research recommendation
    Published
    9 June 2015

  15. NICE encourages further research into the use of a wireless capsule to assess motility of the gastrointestinal tract. Studies should include clear details of patient selection. They should report on the diagnostic accuracy of the procedure in different parts of the gastrointestinal tract, and should provide data on the clinical benefits of the procedure for patients.

    Recommendation ID IPG502/1 Question NICE encourages further research into the use of a wireless capsule to assess motility of the gastrointestinal

    Research recommendation
    Published
    9 June 2015