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Showing 4726 to 4740 of 8314 results

  1. Episcissors-60 show promise for mediolateral episiotomy. But there is currently not enough evidence to support the case for routine adoption in the NHS. Research is recommended to address uncertainties about the efficacy and safety of using Episcissors-60. This research should: - determine if using Episcissors-60 in addition to other care bundle measures is more effective in achieving an optimal episiotomy angle and in preventing episiotomy-related obstetric anal sphincter injuries (OASI) than standard episiotomy scissors - include patient-reported outcome measures - address potential equality considerations by ensuring patients at greatest risk of OASI are recruited - determine the relative cost of using Episcissors-60 compared with standard episiotomy scissors.

    Recommendation ID MTG47/1 Question Episcissors-60 show promise for mediolateral episiotomy. But there is currently not enough evidence

    Research recommendation
    Published
    17 March 2020

  2. Evidence on the progression of X-linked hypophosphataemia (XLH) over time and the long-term benefits of burosumab would also be valuable.

    Recommendation ID HST8/3 Question Evidence on the progression of X-linked hypophosphataemia (XLH) over time and the long-term benefits

    Research recommendation
    Published
    22 March 2019

  3. Further research should ideally be in the form of randomised controlled trials. Details of patient selection, the procedure and long-term outcomes should be reported.

    Recommendation ID IPG766 Question Further research should ideally be in the form of randomised controlled trials. Details of patient selection

    Research recommendation
    Published
    7 August 2023

  4. Evidence on the safety and efficacy of aortic remodelling hybrid stent insertion during surgical repair of an acute type A aortic dissection is limited in quantity and quality. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    Recommendation ID IPG733/01 Question Evidence on the safety and efficacy of aortic remodelling hybrid stent insertion during surgical repair

    Research recommendation
    Published
    7 September 2022

  5. Evidence on the safety and efficacy of biodegradable spacer insertion to reduce rectal toxicity during radiotherapy for prostate cancer is limited in quality. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    Recommendation ID IPG752/01 Question Evidence on the safety and efficacy of biodegradable spacer insertion to reduce rectal toxicity during

    Research recommendation
    Published
    9 March 2023

  6. Evidence on the safety and efficacy of intramedullary distraction for lower limb lengthening is limited in quantity and quality. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page. This guidance is not intended to cover this procedure for bilateral lower limb lengthening for people with short stature.

    Recommendation ID IPG718/01 Question Evidence on the safety and efficacy of intramedullary distraction for lower limb lengthening is limited

    Research recommendation
    Published
    8 April 2022

  7. Evidence on the efficacy and safety of neurostimulation of lumbar muscles for refractory non-specific chronic low back pain is limited in quantity and quality. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    Recommendation ID IPG739/01 Question Evidence on the efficacy and safety of neurostimulation of lumbar muscles for refractory non-specific

    Research recommendation
    Published
    30 September 2022

  8. Evidence on the safety and efficacy of intramedullary distraction for upper limb lengthening is inadequate in quantity and quality. But because this is a rare condition with limited alternative treatments, the procedure can be considered as long as special arrangements for clinical governance, consent, and audit or research are in place. Find out what special arrangements mean on the NICE interventional procedures guidance page. Further research, which could be registry data, should report details of patient  selection, device selection, technique used, procedural outcomes, long-term  outcomes including quality of life, the need for repeat interventions or surgery and complication rates.

    Recommendation ID IPG722/01 Question Evidence on the safety and efficacy of intramedullary distraction for upper limb lengthening is inadequate

    Research recommendation
    Published
    11 May 2022

  9. Evidence on the safety and efficacy of daytime intraoral neuromuscular electrical tongue stimulation using a removable device for obstructive sleep apnoea is inadequate in quality and quantity. So, this procedure should be used only in research. Find out what only in research means on the NICE interventional procedures guidance page.

    Recommendation ID IPG760/1 Question Evidence on the safety and efficacy of daytime intraoral neuromuscular electrical tongue stimulation

    Research recommendation
    Published
    5 May 2023

  10. Evidence on the efficacy of bioresorbable stent implantation to treat coronary artery disease is inadequate. Evidence on its safety has shown an increased risk of serious complications in the longer term. This includes an increased risk of myocardial infarction and death with some types of bioresorbable stents. Therefore, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page.

    Recommendation ID IPG732/01 Question Evidence on the efficacy of bioresorbable stent implantation to treat coronary artery disease is inadequate

    Research recommendation
    Published
    7 September 2022

  11. Evidence on the safety and efficacy of endobronchial nerve ablation for chronic obstructive pulmonary disease (COPD) is inadequate in quantity. Therefore, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page. Further research should be randomised controlled trials comparing the procedure with sham treatment. It should report details of patient selection, and short and long-term functional outcomes including lung functional outcomes, quality of life and patient-reported outcomes, incidence of exacerbations and hospital admissions, and all adverse events.

    Recommendation ID IPG174/01 Question Evidence on the safety and efficacy of endobronchial nerve ablation for chronic obstructive pulmonary

    Research recommendation
    Published
    7 January 2022

  12. Evidence on the safety and efficacy of laparoscopic renal denervation for loin pain haematuria syndrome is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page. Further research should report details of patient selection, technique used and long-term follow-up outcomes

    Recommendation ID IPG709/01 Question Evidence on the safety and efficacy of laparoscopic renal denervation for loin pain haematuria syndrome

    Research recommendation
    Published
    5 November 2021

  13. Evidence on the efficacy of focal resurfacing implants to treat articular cartilage damage in the knee is limited in quality and quantity. Short-term evidence shows no major safety concerns, but long-term evidence on safety is limited in quality and quantity. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    Recommendation ID IPG734/01 Question Evidence on the efficacy of focal resurfacing implants to treat articular cartilage damage in the

    Research recommendation
    Published
    7 September 2022

  14. Evidence on the safety and efficacy of lateral elbow resurfacing for arthritis is limited in quantity and quality. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page. Further research, which could include case series with long-term follow up, should report range of motion, patient-reported outcomes and complications.

    Recommendation ID IPG705/1 Question Evidence on the safety and efficacy of lateral elbow resurfacing for arthritis is limited in quantity

    Research recommendation
    Published
    30 September 2021

  15. Evidence on the safety and efficacy of inducing and maintaining normothermia using temperature modulation devices to improve outcomes after stroke or subarachnoid haemorrhage is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page.

    Recommendation ID IPG701/1 Question Evidence on the safety and efficacy of inducing and maintaining normothermia using temperature modulation

    Research recommendation
    Published
    13 August 2021