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Guidance programme

Advice programme

Showing 4906 to 4920 of 8314 results

  1. What is the effectiveness of oral tacrolimus and systemic (intramuscular/subcutaneous/oral) methotrexate in the induction of remission in mild-to-moderate ulcerative colitis unresponsive to aminosalicylates?

    Recommendation ID NG130/2 Question What is the effectiveness of oral tacrolimus and systemic (intramuscular/subcutaneous/oral) methotrexate

    Research recommendation
    Published
    25 October 2019

  2. Antipyretics: The GDG recommends that studies are conducted in primary care and secondary care to determine whether examination or re-examination after a dose of antipyretic medication is of benefit in differentiating children with serious illness from those with other conditions.

    Recommendation ID NG143/04 Question Antipyretics: The GDG recommends that studies are conducted in primary care and secondary care to determine

    Research recommendation
    Published
    17 December 2021

  3. What is the effectiveness and cost effectiveness of bariatric surgery in achieving weight loss and improving treatment outcomes in people who are unable to receive treatment for other health conditions (such as joint replacement surgery or fertility treatment) because they are living with obesity?

    Recommendation ID CG189/03 Question What is the effectiveness and cost effectiveness of bariatric surgery in achieving weight loss and

    Research recommendation
    Published
    7 September 2023

  4. The effectiveness of pulsatile gonadotrophin-releasing hormone in women with clomifene citrate-resistant polycystic ovary syndrome is uncertain and is therefore not recommended outside a research context. [2004]

    Recommendation ID CG156/7 Question The effectiveness of pulsatile gonadotrophin-releasing hormone in women with clomifene citrate-resistant

    Research recommendation
    Published
    9 June 2015

  5. Symptoms and signs of serious illness: The Guideline Development Group (GDG) recommends a UK-based epidemiological study on the symptoms and signs of serious illness.

    Recommendation ID NG143/01 Question Symptoms and signs of serious illness: The Guideline Development Group (GDG) recommends a UK-based

    Research recommendation
    Published
    17 December 2021

  6. Surveillance programmes for people at increased risk of colorectal cancer:- How effective are colonoscopic surveillance programmes in improving overall survival and cancer-related survival in people at increased risk of colorectal cancer?

    Recommendation ID CG118/1 Question Surveillance programmes for people at increased risk of colorectal cancer:- How effective are colonoscopic

    Research recommendation
    Published
    9 June 2015

  7. Further evidence to address uncertainties about the relative clinical and cost effectiveness of UroLift compared with Rezum, especially in the NHS, would be welcome. This should include: • exploring long-term clinical outcomes and reintervention rates after UroLift • assessing the suitability of UroLift for prostates larger than 80 ml and for those with an obstructive median lobe.

    Recommendation ID MTG58/1 Question Further evidence to address uncertainties about the relative clinical and cost effectiveness of UroLift

    Research recommendation
    Published
    10 August 2021

  8. Evidence on the safety of the swallowable gastric balloon capsule for weight loss shows infrequent but potentially serious adverse events: For people who need to lose weight in the short term for medical reasons, the evidence of efficacy is adequate to support the use of this procedure provided that special arrangements are in place for clinical governance, consent and audit.  Find out  what special arrangements mean on the NICE interventional procedures guidance page . For people who are aiming for long-term weight loss, the evidence on efficacy is inadequate in quantity and quality, so the procedure should only be used in the context of research.   Find out  what only in research means on the NICE interventional procedures guidance page .

    Recommendation ID IPG684/1 Question Evidence on the safety of the swallowable gastric balloon capsule for weight loss shows infrequent

    Research recommendation
    Published
    22 January 2021

  9. The evidence for treating an acute migraine attack is adequate but, for treating subsequent attacks, is limited in quality and quantity. So, for treating acute migraine, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page . The evidence for preventing migraine is inadequate in quality. So, for preventing migraine, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page.

    Recommendation ID IPG740/01 Question The evidence for treating an acute migraine attack is adequate but, for treating subsequent attacks

    Research recommendation
    Published
    7 November 2022

  10. The health-related quality-of-life evidence of patients with perianal fistulas is also lacking, therefore further research is recommended. Any research should measure the effect of treatment using preference-based measures (such as use of the EQ-5D questionnaire).

    Recommendation ID TA556/2 Question The health-related quality-of-life evidence of patients with perianal fistulas is also lacking, therefore

    Research recommendation
    Published
    19 March 2019

  11. The evidence on efficacy of nerve transfer to partially restore upper limb function in tetraplegia is limited in quantity. There are no major safety concerns. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research.

    Recommendation ID IPG610/1 Question The evidence on efficacy of nerve transfer to partially restore upper limb function in tetraplegia

    Research recommendation
    Published
    21 November 2018

  12. The physical health benefits of discontinuing antipsychotic medication:- What are the short- and long-term benefits to physical health of guided medication discontinuation and/or reduction in first episode psychosis and can this be achieved without major risks?

    Recommendation ID CG178/3 Question The physical health benefits of discontinuing antipsychotic medication:- What are the short- and long-term

    Research recommendation
    Published
    9 June 2015

  13. The evidence on transvaginal laser therapy for stress urinary incontinence does not show any short-term safety concerns. Evidence on long-term safety andefficacy is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of research. Find out what only in research means onthe NICE interventional procedures guidance page.

    Recommendation ID IPG696/1 Question The evidence on transvaginal laser therapy for stress urinary incontinence does not show any short-term

    Research recommendation
    Published
    10 August 2021

  14. There have been no head-to-head trials of rivaroxaban compared with a low molecular weight heparin for people who have cancer and experience an acute pulmonary embolism or deep vein thrombosis. As in NICE technology appraisal guidance 261 it is recommended that further research should be carried out.

    Recommendation ID TA287/1 Question There have been no head-to-head trials of rivaroxaban compared with a low molecular weight heparin for

    Research recommendation
    Published
    9 June 2015

  15. There is a need for additional research on the management of bleeds that occur while people are receiving apixaban, rivaroxaban or dabigatran etexilate, as there are no antidotes or established treatments to stop active bleeding for these agents.

    Recommendation ID TA275/1 Question There is a need for additional research on the management of bleeds that occur while people are receiving

    Research recommendation
    Published
    9 June 2015