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Area of interest

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Type

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Last updated

Guidance programme

Advice programme

Showing 6046 to 6060 of 8314 results

  1. What overall osmolality (or concentration of calcium and glucose/dextrose) in parenteral nutrition can determine whether to administer centrally or peripherally?

    Recommendation ID NG154/4 Question What overall osmolality (or concentration of calcium and glucose/dextrose) in parenteral nutrition can

    Research recommendation
    Published
    17 March 2020

  2. What is the optimal timeframe for starting parenteral nutrition in term babies who are critically ill or require surgery?

    Recommendation ID NG154/3 Question What is the optimal timeframe for starting parenteral nutrition in term babies who are critically ill

    Research recommendation
    Published
    17 March 2020

  3. What is the optimal ratio of non-nitrogen energy to nitrogen in parenteral nutrition for preterm and term babies?

    Recommendation ID NG154/2 Question What is the optimal ratio of non-nitrogen energy to nitrogen in parenteral nutrition for preterm and

    Research recommendation
    Published
    17 March 2020

  4. What are the information and support needs of parents and carers with babies on parenteral nutrition?

    Recommendation ID NG154/1 Question What are the information and support needs of parents and carers with babies on parenteral nutrition

    Research recommendation
    Published
    17 March 2020

  5. Neuropathic pain relief:- Does early treatment with a centrally acting analgesic (for example pregabalin) reduce the frequency or severity of neuropathic pain in people with spinal cord injury?

    Recommendation ID NG41/1 Question Neuropathic pain relief:- Does early treatment with a centrally acting analgesic (for example pregabalin)

    Research recommendation
    Published
    4 April 2016

  6. Newly diagnosed seizures (focal and generalised) – monotherapy: How do the newer AEDs compare in efficacy to the standard AEDs in the treatment of newly diagnosed epilepsy? Focal seizures: carbamazepine, eslicarbazepine acetate, lacosamide, lamotrigine, levetiracetam, pregabalin  and zonisamide. Generalised seizures: lamotrigine, levetiracetam, sodium valproate and zonisamide.

    Recommendation ID CG137/1 Question Newly diagnosed seizures (focal and generalised) – monotherapy: How do the newer AEDs compare in efficacy

    Research recommendation
    Published
    13 August 2021

  7. NICE agreed that further research was needed because there is currently no clinical- or cost-effectiveness evidence evaluating the use of Holoclar in both eyes in bilateral patients. The committee was aware of the ongoing HOLOCORE trial which is recruiting both unilateral and bilateral patients, but only evaluates the success of a second transplant in 1 eye rather than transplant success in both eyes.

    Recommendation ID TA467/1 Question NICE agreed that further research was needed because there is currently no clinical- or cost-effectiveness

    Research recommendation
    Published
    15 October 2018

  8. NICE agreed that further research would be of value to investigate factors which can predict the likelihood of rapid progression of disease and response to treatment with biological DMARDs. Factors to investigate include:- persistent elevation of inflammatory markers (such as C-reactive protein [CRP]) and- presence of erosions on X-ray and- positive for anti-citrullinated protein antibodies (ACPA).

    Recommendation ID TA375/1 Question NICE agreed that further research would be of value to investigate factors which can predict the likelihood

    Research recommendation
    Published
    15 March 2016

  9. NICE also considered the role of FeNO in guiding inhaled corticosteroid dosing through stepping-up and stepping-down protocols. It accepted there is a need for more evidence on which protocols offer the safest and most optimal asthma management when used in UK clinical practice. Therefore, further studies are recommended, with consideration for the different protocols and cut-off points that may be necessary in different populations.

    Recommendation ID DG12/3 Question NICE also considered the role of FeNO in guiding inhaled corticosteroid dosing through stepping-up and

    Research recommendation
    Published
    9 June 2015

  10. NICE also considered the role of FeNO measurement in asthma management. It accepted that currently available evidence on the use of FeNO measurement in asthma management is unclear on whether benefits of treatment are maintained long-term. NICE concluded that long-term studies following patients for several years could address this gap.

    Recommendation ID DG12/2 Question NICE also considered the role of FeNO measurement in asthma management. It accepted that currently available

    Research recommendation
    Published
    9 June 2015

  11. What are the long-term risks of mesh surgery compared with non-mesh surgery for stress urinary incontinence and pelvic organ prolapse in women?

    Recommendation ID NG123/5 Question What are the long-term risks of mesh surgery compared with non-mesh surgery for stress urinary incontinence

    Research recommendation
    Published
    21 June 2019

  12. Long-term safety of ovarian stimulation and ovulation induction for women:- Is there an association between ovulation induction or ovarian stimulation and adverse long-term (over 20 years) effects in women in the UK?

    Recommendation ID CG156/4 Question Long-term safety of ovarian stimulation and ovulation induction for women:- Is there an association

    Research recommendation
    Published
    9 June 2015

  13. Long-term safety of tenofovir disoproxil in chronic hepatitis B:- Further research should be undertaken to determine the long-term safety of tenofovir disoproxil, including the risk of clinically significant hypophosphataemia and related bone toxicity, in people with chronic hepatitis B. The cost effectiveness of routine monitoring for phosphate loss and bone disease in people with chronic hepatitis B who are receiving tenofovir disoproxil treatment needs further evaluation.

    Recommendation ID CG165/3 Question Long-term safety of tenofovir disoproxil in chronic hepatitis B:- Further research should be undertaken

    Research recommendation
    Published
    9 June 2015

  14. Magnesium sulfate for neuroprotection: bolus plus infusion compared with bolus alone:- What is the clinical effectiveness of a bolus plus infusion of magnesium sulfate compared with a bolus alone for preventing neurodevelopmental injury in babies born preterm?

    Recommendation ID NG25/4 Question Magnesium sulfate for neuroprotection: bolus plus infusion compared with bolus alone:- What is the clinical

    Research recommendation
    Published
    11 December 2015

  15. Maintaining benefits after successful treatment of anorexia nervosa:- What factors (including comorbidities, personal, social and demographic factors, treatment type,and subsequent relapse prevention interventions) are associated with continued benefit after successful treatment for anorexia nervosa?

    Recommendation ID NG69/5 Question Maintaining benefits after successful treatment of anorexia nervosa:- What factors (including comorbidities

    Research recommendation
    Published
    12 October 2018