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This guidance has been updated and replaced by NICE's technology appraisal guidance on bevacizumab (originator and biosimilars) with fluoropyrimidine-based chemotherapy for metastatic colorectal cancer (TA1136).
Leadless cardiac pacemaker implantation for bradyarrhythmias (HTG484)
This guidance has been updated and replaced by NICE HealthTech guidance 770.
Selinexor for treating unresectable dedifferentiated advanced liposarcoma [ID3825]
Discontinued Reference number: GID-TA10694
Discontinued Reference number: GID-TA10843
This guidance has been withdrawn because Cartiva Synthetic Cartilage Implant (SCI) has been recalled, and the evidence for this guidance was based solely on Cartiva SCI. More information is available in the field safety notice issued by Stryker. Surgeons are advised not to implant this device, to return any unused devices to Stryker and to consider reviewing any patients who have had Cartiva SCI. NICE will consider issuing new guidance on synthetic cartilage implant insertion for first metatarsophalangeal joint osteoarthritis (hallux rigidus) if evidence using an appropriately CE-marked device becomes available.
In development Reference number: GID-TA11655 Expected publication date: TBC
Discontinued Reference number: GID-MT81
Discontinued Reference number: GID-TA10026
In development Reference number: GID-TA11908 Expected publication date: TBC
Nivolumab + Brentuximab vedotin for Hodgkin lymphoma [ID6691]
In development Reference number: GID-TA11909 Expected publication date: TBC
Eteplirsen for treating Duchenne muscular dystrophy [ID1003]
Discontinued Reference number: GID-HST10007
Drisapersen for the first-line treatment of Duchenne's muscular dystrophy [ID911]
Discontinued Reference number: GID-HST10004
Discontinued Reference number: GID-DT9
Intrathecal idursulfase for treating Mucopolysaccharidosis type II ID1223
Discontinued Reference number: GID-HST10019
Arimoclomol for treating Niemann-Pick disease Type C [ID1312]
In development Reference number: GID-HST10037 Expected publication date: TBC