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Guidance programme

Advice programme

Showing 5536 to 5550 of 8219 results

  1. The effects of stopping and/or switching drug treatments to control blood glucose levels: In adults with type 2 diabetes, what are the effects of stopping and/or switching drug treatments to control blood glucose levels, and what criteria should inform the decision?

    Recommendation ID NG28/01 Question The effects of stopping and/or switching drug treatments to control blood glucose levels: In adults

    Research recommendation
    Published
    16 December 2021

  2. Long-term outcomes associated with blood glucose lowering agents: In adults with type 2 diabetes, what are the long‑term effects of blood glucose lowering therapies such as dipeptidyl peptidase‑4 (DPP‑4) inhibitors, sodium–glucose cotransporter‑2 (SGLT2) inhibitors and meglitinides?

    Recommendation ID NG28/04 Question Long-term outcomes associated with blood glucose lowering agents: In adults with type 2 diabetes, what

    Research recommendation
    Published
    16 December 2021

  3. Pilon fractures: In adults with closed pilon fractures, what method of fixation provides the best clinical and cost effectiveness outcomes as assessed by function and incidence of major complications at 2 years (stratified for timing of definitive surgery early [under 36 hours] versus later [over 36 hours])?

    Recommendation ID NG37/03 Question Pilon fractures: In adults with closed pilon fractures, what method of fixation provides the best clinical

    Research recommendation
    Published
    12 December 2022

  4. In adults with common bile duct stones, should laparoscopic cholecystectomy be performed early (within 2 weeks of bile duct clearance), or should it be delayed (until 6 weeks after bile duct clearance)?

    Recommendation ID CG188/4 Question In adults with common bile duct stones, should laparoscopic cholecystectomy be performed early (within

    Research recommendation
    Published
    9 June 2015

  5. Non-metformin-based drug treatment combinations to control blood glucose levels: In adults with type 2 diabetes, what treatment combinations (for example, glucagon‑like peptide‑1 [GLP‑1] mimetics and insulin combination therapy with meglitinides) are most effective when initial drug treatment with non‑metformin monotherapy fails to adequately control blood glucose levels?

    Recommendation ID NG28/02 Question Non-metformin-based drug treatment combinations to control blood glucose levels: In adults with type

    Research recommendation
    Published
    16 December 2021

  6. Indicators and thresholds for referral for cataract surgery:- What is the association between preoperative vision- and health-related quality of life, and postoperative vision-related quality of life, health-related quality of life, and self-reported postoperative improvement?

    Recommendation ID NG77/3 Question Indicators and thresholds for referral for cataract surgery:- What is the association between preoperative

    Research recommendation
    Published
    6 November 2018

  7. Individual versus group CBT for children and young people with social anxiety disorder:- What is the clinical and cost effectiveness of individual and group CBT for children and young people with social anxiety disorder?

    Recommendation ID CG159/4 Question Individual versus group CBT for children and young people with social anxiety disorder:- What is the

    Research recommendation
    Published
    9 June 2015

  8. What is the clinical and cost effectiveness of prednisolone compared with aminosalicylates for the induction of remission for people with moderate ulcerative colitis?

    Recommendation ID NG130/4 Question What is the clinical and cost effectiveness of prednisolone compared with aminosalicylates for the induction

    Research recommendation
    Published
    25 October 2019

  9. What is the clinical and cost effectiveness of prednisolone plus an aminosalicylate compared with beclometasone plus an aminosalicylate for induction of remission for people with moderate ulcerative colitis?

    Recommendation ID NG130/5 Question What is the clinical and cost effectiveness of prednisolone plus an aminosalicylate compared with beclometasone

    Research recommendation
    Published
    25 October 2019

  10. What are the benefits, risks and cost effectiveness of methotrexate, ciclosporin, tacrolimus, adalimumab and infliximab compared with each other and with placebo for induction of remission for people with subacute ulcerative colitis that is refractory to systemic corticosteroids?

    Recommendation ID NG130/6 Question What are the benefits, risks and cost effectiveness of methotrexate, ciclosporin, tacrolimus, adalimumab

    Research recommendation
    Published
    25 October 2019

  11. Further research is recommended to help address remaining clinical and cost-effectiveness uncertainties for esketamine, summarised in section 3.36 .

    Recommendation ID TA854/01 Question Further research is recommended to help address remaining clinical and cost-effectiveness uncertainties

    Research recommendation
    Published
    6 January 2023

  12. Further research is recommended to resolve the uncertainties about the long-term clinical effectiveness of darvadstrocel compared with standard care. In particular, estimates of long-term remission rates (minimum of 2 years' follow-up) in Crohn's disease with perianal fistulas are needed.

    Recommendation ID TA556/1 Question Further research is recommended to resolve the uncertainties about the long-term clinical effectiveness

    Research recommendation
    Published
    19 March 2019

  13. Further research is recommended to resolve uncertainties about the clinical effectiveness of degarelix compared with luteinising hormone-releasing hormone (LHRH) agonists such as leuprorelin, goserelin and triptorelin for treating advanced hormone-dependent prostate cancer, particularly in subgroups of people with preexisting cardiovascular disease, people with skeletal (including spinal) metastases and people with impending ureteric and urethral obstruction. Research should be planned as part of well-conducted randomised clinical trials.

    Recommendation ID TA404/1 Question Further research is recommended to resolve uncertainties about the clinical effectiveness of degarelix

    Research recommendation
    Published
    17 October 2016

  14. Pelvic floor muscle training for preventing pelvic floor dysfunction in young women: Is pelvic floor muscle training for young women (between 12 and 17 years) effective in preventing pelvic floor dysfunction?

    Recommendation ID NG210/02 Question Pelvic floor muscle training for preventing pelvic floor dysfunction in young women: Is pelvic floor

    Research recommendation
    Published
    7 January 2022

  15. Electroacupuncture: Is electroacupuncture a clinically and cost-effective treatment for any subgroup of people with osteoarthritis?

    Recommendation ID NG226/07 Question Electroacupuncture: Is electroacupuncture a clinically and cost-effective treatment for any subgroup

    Research recommendation
    Published
    7 November 2022