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This evidence summary has been updated and replaced by NICE evidence summary: new medicines 61.
Excessive daytime sleepiness in Parkinson's disease: modafinil (ESUOM48)
This evidence summary has been updated and replaced by NICE guideline NG71.
Hormone-sensitive metastatic prostate cancer: docetaxel (ESUOM50)
This evidence summary has been updated and replaced by NICE guideline NG131.
This evidence summary has been withdrawn following updated information in the summary of product characteristics on the off-label use of sildenafil (Revatio) in neonates with persistent pulmonary hypertension of the newborn.
Attention deficit hyperactivity disorder in children and young people: clonidine (ESUOM8)
This evidence summary has been updated and replaced by NICE guideline NG87.
This advice has been updated and replaced by NICE guideline NG220.
This guideline has been updated and replaced by NICE guideline NG101.
Cox-II inhibitors for the treatment of osteoarthritis and rheumatoid arthritis (TA27)
This guidance has been replaced by NICE guideline CG59 and NICE guideline CG79.
This guidance has been updated and replaced by NICE technology appraisal guidance 301.
This guidance has been updated and replaced by the NICE guideline on asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN).
This guidance has been updated and replaced by NICE technology appraisal guidance 908.
Pegloticase for treating severe debilitating chronic tophaceous gout (TA291)
The guidance has been withdrawn because pegloticase (Krystexxa) no longer has a marketing authorisation. See the European Medicines Agency product information.
This guidance has been updated and replaced by NICE technology appraisal guidance TA421.
This guideance has been updated and replaced by NICE technology appraisal guidance 422.
We have withdrawn this guidance. Inceptua has stopped marketing Ocriplasmin (Jetrea) and its marketing authorisation has been withdrawn.