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Crizanlizumab for preventing sickle cell crises in sickle cell disease (TA743)
NICE has withdrawn this guidance. Novartis will stop marketing crizanlizumab (Adakveo) because its marketing authorisation has been withdrawn by the Medicines and Healthcare products Regulatory Agency (MHRA). Novartis has issued a direct letter to healthcare professionals specialising in haematology. No new people will start taking crizanlizumab in the UK. Healthcare professionals should discuss alternative treatment options with people currently having crizanlizumab.
Fedratinib for treating disease-related splenomegaly or symptoms in myelofibrosis (TA756)
This guidance has been updated and replaced by NICE technology appraisal guidance 1018.
Fostamatinib for treating refractory chronic immune thrombocytopenia (TA759)
This guidance has been updated and replaced by NICE technology appraisal guidance 835.
This guideline has been updated and replaced by NICE guideline CG137.
Selpercatinib for previously treated RET fusion-positive advanced non-small-cell lung cancer (TA760)
This guidance has been updated and replaced by NICE technology appraisal guidance TA1042
This guidance has been updated and replaced by NICE technology appraisal guidance 1043.
This guidance has been updated and replaced by NICE technology appraisal guidance 1040.
This guidance has been updated and replaced by NICE technology appraisal guidance 1075.
The clinical effectiveness and cost effectiveness of anakinra for rheumatoid arthritis (TA72)
This appraisal has been updated and replaced by NICE guideline CG79.
This guidance has been updated and replaced by NICE technology appraisal guidance 1110.
This guidance has been updated and replaced by NICE technology appraisal guidance 887.
Atezolizumab for adjuvant treatment of resected non-small-cell lung cancer (TA823)
This guidance has been updated and replaced by NICE technology appraisal guidance 1071.
This guideline has been updated and replaced by NICE guideline CG137.
This guidance has been withdrawn because the simple discount patient access scheme for QuiremSpheres has been withdrawn.
Immunosuppressive therapy for renal transplantation in children and adolescents (TA99)
This guidance has been updated and replaced by NICE technology appraisal guidance 482.