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Guidance programme

Advice programme

Showing 5151 to 5200 of 8238 results

  1. Psychological interventions to manage chronic headache disorders:- Does a psychological intervention such as cognitive behavioural therapy (CBT) improve headache outcomes and quality of life for people with chronic headache disorders?

    Recommendation ID CG150/4 Question Psychological interventions to manage chronic headache disorders:- Does a psychological intervention

  2. Psychological support needs:- A qualitative study should be undertaken to evaluate information and support interventions to address psychological needs at different points in the care pathway for people with pancreatic cancer.

    Recommendation ID NG85/5 Question Psychological support needs:- A qualitative study should be undertaken to evaluate information and support

  3. What is the clinical and cost effectiveness, post-treatment and at longer-term follow‑up, of psychological therapies in children aged 5 to 11 years with mild or moderate to severe depression?

    Recommendation ID NG134/1 Question What is the clinical and cost effectiveness, post-treatment and at longer-term follow‑up, of psychological

  4. Psychosocial interventions for people with more severe learning disabilities:- For people with more severe learning disabilities, what is the clinical and cost effectiveness of psychosocial interventions to treat mental health problems?

    Recommendation ID NG54/5 Question Psychosocial interventions for people with more severe learning disabilities:- For people with more severe

  5. What are the risks that predict the development of blood-borne virus infections in people with complex psychosis in the UK?

    Recommendation ID NG181/11 Question What are the risks that predict the development of blood-borne virus infections in people with complex

  6. Can risk of contrast-induced acute kidney injury be stratified by eGFR thresholds?

    Recommendation ID NG148/1 Question Can risk of contrast-induced acute kidney injury be stratified by eGFR thresholds? Any explanatory

  7. Selective dorsal rhizotomy:- Does selective dorsal rhizotomy followed by intensive rehabilitation performed between the ages of 3 and 9 years in children who are at Gross Motor Function Classification System (GMFCS) level II or III result in good community mobility as a young adult?

    Recommendation ID CG145/5 Question Selective dorsal rhizotomy:- Does selective dorsal rhizotomy followed by intensive rehabilitation performed

  8. What is the effectiveness and cost effectiveness of routinely performing contrast-enhanced brain CT at the time of initial diagnosis and/or staging CT?

    Recommendation ID NG122/3 Question What is the effectiveness and cost effectiveness of routinely performing contrast-enhanced brain CT

  9. Selective internal radiation therapy for unresectable colorectal metastases in the liver

    Recommendation ID IPG672/1 Question Selective internal radiation therapy for unresectable colorectal metastases in the liver

  10. What is the clinical and cost effectiveness of selenium for people with subclinical hypothyroidism?

    Recommendation ID NG145/11 Question What is the clinical and cost effectiveness of selenium for people with subclinical hypothyroidism

  11. Routine outcome measurement:- In people with a common mental health disorder, what is the clinical utility of routine outcome measurement and is it cost effective compared with standard care?

    Recommendation ID CG123/4 Question Routine outcome measurement:- In people with a common mental health disorder, what is the clinical utility

  12. Safety and efficacy of antimuscarinics:- What is the safety and efficacy of more recently developed antimuscarinics compared with (a) placebo/usual care and (b) other antimuscarinics in the treatment of neurogenic lower urinary tract dysfunction?

    Recommendation ID CG148/1 Question Safety and efficacy of antimuscarinics:- What is the safety and efficacy of more recently developed

  13. Self-management:- Do structured psoriasis-focused self-management programmes improve patient confidence, wellbeing and disease control compared with standard care?

    Recommendation ID CG153/4 Question Self-management:- Do structured psoriasis-focused self-management programmes improve patient confidence

  14. Safety and efficacy of botulinum toxin:- What is the safety and efficacy of botulinum toxin compared with (a) usual care, (b) antimuscarinics and (c) augmentation cystoplasty in people with neurogenic lower urinary tract dysfunction?

    Recommendation ID CG148/2 Question Safety and efficacy of botulinum toxin:- What is the safety and efficacy of botulinum toxin compared

  15. Self-management support for people with mental health difficulties:- Which interventions are effective in supporting self-management for people with mental health difficulties who also have a physical condition and are moving into and out of general inpatient hospital settings?

    Recommendation ID NG27/2 Question Self-management support for people with mental health difficulties:- Which interventions are effective

  16. Safety and safeguarding:- What safeguarding practices are most effective in improving outcomes for people using services?

    Recommendation ID NG21/5 Question Safety and safeguarding:- What safeguarding practices are most effective in improving outcomes for people

  17. Self-management:- What is the impact of different early intervention-focused approaches to self-management on outcomes for older people with social care needs and multiple long-term conditions?

    Recommendation ID NG22/5 Question Self-management:- What is the impact of different early intervention-focused approaches to self-management

  18. Self-monitoring strategies:- Does earlier detection of the incidence of late AMD (wet active) by self-monitoring in people diagnosed with early AMD, indeterminate AMD or late AMD (dry) lead to earlier treatment and better long-term outcomes?

    Recommendation ID NG82/5 Question Self-monitoring strategies:- Does earlier detection of the incidence of late AMD (wet active) by self-monitoring

  19. Saliva:- How is excessive drooling of saliva (sialorrhoea) managed in people with motor neurone disease (MND)?

    Recommendation ID NG42/4 Question Saliva:- How is excessive drooling of saliva (sialorrhoea) managed in people with motor neurone disease

  20. Screening assessment tools:- Develop reliable and valid screening assessment tools for attachment and sensitivity that can be made available and used in routine health, social care and education settings.

    Recommendation ID NG26/1 Question Screening assessment tools:- Develop reliable and valid screening assessment tools for attachment and

  21. What is the most accurate prenatal screening marker for TAPS, including middle cerebral artery peak systolic velocity (MCA‑PSV)?

    Recommendation ID NG137/1 Question What is the most accurate prenatal screening marker for TAPS, including middle cerebral artery peak

  22. Serological testing in people who have IgA deficiency:- What is the sensitivity and specificity of IgG tissue transglutaminase (tTG), IgG endomysial antibodies (EMA) and IgG deamidated gliadin peptide (DGP) tests in detecting coeliac disease in people with IgA deficiency?

    Recommendation ID NG20/1 Question Serological testing in people who have IgA deficiency:- What is the sensitivity and specificity of IgG

  23. Serological testing in people who test negative for anti-transglutaminase:- What is the sensitivity and specificity of IgA EMA and IgA DGP tests in detecting coeliac disease inpeople who test negative for IgA tTG?

    Recommendation ID NG20/2 Question Serological testing in people who test negative for anti-transglutaminase:- What is the sensitivity and

  24. Management by remote assessment: The GDG recommends that a UK study is undertaken to determine the validity of symptoms reported on remote assessment for children with fever.

    Recommendation ID NG143/02 Question Management by remote assessment: The GDG recommends that a UK study is undertaken to determine the

  25. The consequences and costs of poor transition:- What are the consequences and the costs of young people with ongoing needs not making a transition into adult services, or being poorly supported through the process?

    Recommendation ID NG43/4 Question The consequences and costs of poor transition:- What are the consequences and the costs of young people

  26. Diagnosis: The GDG recommends that a UK study of the performance characteristics and cost-effectiveness of procalcitonin versus C-reactive protein in identifying serious bacterial infection in children with fever without apparent source be carried out.

    Recommendation ID NG143/03 Question Diagnosis: The GDG recommends that a UK study of the performance characteristics and cost-effectiveness

  27. What is the effectiveness and cost effectiveness of bariatric surgery in achieving weight loss and maintaining a healthier weight in adults from minority ethnic family backgrounds who are living with obesity?

    Recommendation ID CG189/04 Question What is the effectiveness and cost effectiveness of bariatric surgery in achieving weight loss and

  28. Management according to risk of serious illness: The GDG recommends that research is carried out on referral patterns between primary and secondary care for children with fever, so the health economic impact of this and future guidelines can be estimated.

    Recommendation ID NG143/07 Question Management according to risk of serious illness: The GDG recommends that research is carried out on

  29. What is the effectiveness of oral tacrolimus and systemic (intramuscular/subcutaneous/oral) methotrexate in the induction of remission in mild-to-moderate ulcerative colitis unresponsive to aminosalicylates?

    Recommendation ID NG130/2 Question What is the effectiveness of oral tacrolimus and systemic (intramuscular/subcutaneous/oral) methotrexate

  30. Antipyretics: The GDG recommends that studies are conducted in primary care and secondary care to determine whether examination or re-examination after a dose of antipyretic medication is of benefit in differentiating children with serious illness from those with other conditions.

    Recommendation ID NG143/04 Question Antipyretics: The GDG recommends that studies are conducted in primary care and secondary care to determine

  31. The effectiveness of pulsatile gonadotrophin-releasing hormone in women with clomifene citrate-resistant polycystic ovary syndrome is uncertain and is therefore not recommended outside a research context. [2004]

    Recommendation ID CG156/7 Question The effectiveness of pulsatile gonadotrophin-releasing hormone in women with clomifene citrate-resistant

  32. Symptoms and signs of serious illness: The Guideline Development Group (GDG) recommends a UK-based epidemiological study on the symptoms and signs of serious illness.

    Recommendation ID NG143/01 Question Symptoms and signs of serious illness: The Guideline Development Group (GDG) recommends a UK-based

  33. Surveillance programmes for people at increased risk of colorectal cancer:- How effective are colonoscopic surveillance programmes in improving overall survival and cancer-related survival in people at increased risk of colorectal cancer?

    Recommendation ID CG118/1 Question Surveillance programmes for people at increased risk of colorectal cancer:- How effective are colonoscopic

  34. The health-related quality-of-life evidence of patients with perianal fistulas is also lacking, therefore further research is recommended. Any research should measure the effect of treatment using preference-based measures (such as use of the EQ-5D questionnaire).

    Recommendation ID TA556/2 Question The health-related quality-of-life evidence of patients with perianal fistulas is also lacking, therefore

  35. The physical health benefits of discontinuing antipsychotic medication:- What are the short- and long-term benefits to physical health of guided medication discontinuation and/or reduction in first episode psychosis and can this be achieved without major risks?

    Recommendation ID CG178/3 Question The physical health benefits of discontinuing antipsychotic medication:- What are the short- and long-term

  36. There is a need for additional research on the management of bleeds that occur while people are receiving apixaban, rivaroxaban or dabigatran etexilate, as there are no antidotes or established treatments to stop active bleeding for these agents.

    Recommendation ID TA275/1 Question There is a need for additional research on the management of bleeds that occur while people are receiving