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Multiple sclerosis: Management of multiple sclerosis in primary and secondary care (CG8)
This guidance has been updated and replaced by NICE guideline CG186.
Early and locally advanced breast cancer: diagnosis and treatment (CG80)
This guideline has been updated and replaced by NICE guideline NG101.
This guidance has been updated and replaced by NICE guideline CG178. This guideline updates and replaces NICE guideline CG1.
November 2025: We have withdrawn this quality standard following the launch of new NICE guidelines on suspected sepsis in people aged 16 or over, suspected sepsis in under 16s and suspected sepsis in pregnant or recently pregnant people. This quality standard is now partially replaced by NICE's quality standard on suspected sepsis in over 16s. Quality standards for sepsis in people under 16 and for people who are or have recently been pregnant will publish when paediatric and maternity early warning score tools are reviewed for the next update to the NICE guidelines in 2026. For any queries, please contact qualitystandards@nice.org.uk.
This quality standard has been withdrawn. Specialist neonatal care is covered in the NICE quality standards for specialist neonatal respiratory care for babies born pre-term, developmental follow-up of children and young people born preterm, maternal and child nutrition and postnatal care.
This quality standard has been updated and replaced by NICE quality standard 211.
This quality standard has been updated and replaced by NICE quality standard 211.
Venous thromboembolism in adults: diagnosis and management (QS29)
This quality standard has been updated and replaced by NICE quality standard QS201.
Venous thromboembolism in adults: reducing the risk in hospital (QS3)
This quality standard has been updated and replaced by NICE quality standard QS201.
This quality standard has been updated and replaced by NICE quality standard 184.
This quality standard is updated and replaced by the quality standards on type 1 diabetes in adults (QS208) and type 2 diabetes in adults (QS209).
This quality standard has been updated and replaced by NICE quality standard 212.
This quality standard has been updated and replaced by NICE quality standard 207.
This quality standard has been updated and replaced by NICE quality standard 180.
In development Reference number: GID-TA11805 Expected publication date: TBC
This guidance has been updated and replaced by NICE guideline NG130.
Myocardial infarction with ST-segment elevation: acute management (CG167)
This guideline has been updated and replaced by NICE guideline NG185.
Acute kidney injury: prevention, detection and management (CG169)
This guidance has been updated and replaced by NICE guideline NG148.
Dyspepsia: Management of dyspepsia in adults in primary care (CG17)
This guidance has been updated and replaced by NICE guideline CG184.
This guideline has been updated and replaced by NICE guideline NG123.
This guideline has been updated and replaced by NICE guideline NG185.
This guideline has been updated and replaced by NICE guideline NG131.
This guideline has been updated and replaced by the NICE guideline on head injury: assessment and management (NG232).
This guidance has been updated and replaced by NICE guideline NG226.
This guidance has been updated and replaced by NICE guideline CG34.
This guidance has been updated and replaced by NICE guideline NG196.
Cardiovascular disease: risk assessment and reduction, including lipid modification (CG181)
This guideline has been updated and replaced by NICE guideline NG238.
Chronic kidney disease in adults: assessment and management (CG182)
This guidance has been updated and replaced by NICE guideline NG203.
This guidance has been updated and replaced by NICE guideline NG220.
In development Reference number: GID-TA10745 Expected publication date: 17 July 2024
In development Reference number: GID-TA11491 Expected publication date: TBC
In development Reference number: GID-TA11511 Expected publication date: TBC
In development Reference number: GID-TA11406 Expected publication date: TBC
In development Reference number: GID-TA11352 Expected publication date: TBC
Stereotactic radiosurgery for trigeminal neuralgia using the gamma knife (IPG85)
Interventional procedures, IPG85 - Issued: August 2004 --> This guidance has been updated and replaced by NICE HealthTech guidance 608.
Baloxavir marboxil for treating influenza in babies under 1 year [ID6555]
Discontinued Reference number: GID-TA11712
Baloxavir marboxil for treating and preventing influenza in people 3 weeks to 11 years [ID6554]
In development Reference number: GID-TA11732 Expected publication date: TBC
Intramedullary distraction for lower limb lengthening (IPG197)
This guidance has been updated and replaced by NICE HealthTech guidance 613.
This guideline has been updated and replaced by NICE guideline NG101.
Inhaled insulin for the treatment of type 1 and type 2 diabetes (TA113)
In January 2008, Pfizer ceased production of its inhaled insulin product Exubera. NICE technology appraisal 113 on inhaled insulin for diabetes (types I and II) has therefore been made obsolete. Pfizer have been letting doctors know that they should begin moving their patients off Exubera and onto other medicines that control high blood sugar levels. If you are worried about how you should control your blood sugar levels as a result of this announcement, you should contact your doctor as soon as possible to discuss your options for other blood sugar lowering medications. 25 January 2008
Glycoprotein IIb/IIIa inhibitors in the treatment of acute coronary syndromes (TA12)
This guidance has been replaced by NICE technology appraisal guidance 47.
Cardiac resynchronisation therapy for the treatment of heart failure (TA120)
This guidance has been updated and replaced by NICE technology appraisal guidance 314.
Alteplase for the treatment of acute ischaemic stroke (TA122)
This guidance has been updated and replaced by NICE technology appraisal guidance 264 issued in September 2012.
Infliximab for subacute manifestations of ulcerative colitis (TA140)
This guidance has been updated and replaced by NICE technology appraisal guidance 329.
This appraisal has been updated and replaced by NICE technology appraisal guidance 195.
Epoetin alfa, epoetin beta and darbepoetin alfa for cancer treatment-induced anaemia (TA142)
This guidance has been replaced by NICE technology appraisal guidance 323.
Adalimumab, etanercept and infliximab for ankylosing spondylitis (TA143)
This guidance has been updated and replaced by NICE technology appraisal guidance 383.
Rimonabant for the treatment of overweight and obese adults (TA144)
This appraisal has been withdrawn. This is because the marketing authorisation for rimonabant was withdrawn on 16 January 2009.
Bevacizumab for the first-line treatment of metastatic breast cancer (TA147)
This appraisal has been updated and replaced by NICE technology appraisal 214.
This guidance has been replaced by NICE technology appraisal guidance 58 [Replaced by NICE technology appraisal guidance 168].