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This guidance has been updated and replaced by NICE technology appraisal guidance TA421.
This guideance has been updated and replaced by NICE technology appraisal guidance 422.
We have withdrawn this guidance. Inceptua has stopped marketing Ocriplasmin (Jetrea) and its marketing authorisation has been withdrawn.
Bosutinib for previously treated chronic myeloid leukaemia (TA299)
This guidance has been updated and replaced by NICE technology appraisal guidance 401.
This guidance has been replaced by NICE technology appraisal guidance 93 [Replaced by NICE guideline CG131].
The guidance has been withdrawn because Janssen withdrew their marketing authorisation on 1 May 2018. The availability of direct-acting antiviral combination treatments for hepatitis C has reduced the use of simeprevir, so the company has decided to discontinue it.
This appraisal has been withdrawn. This is because the marketing authorisation for sipuleucel-T was withdrawn on 19 May 2015.
This guidance has been replaced by NICE technology appraisal guidance 55.
This guidance has been updated and replaced by NICE guideline NG219.
Pirfenidone for treating idiopathic pulmonary fibrosis (TA282)
This guidance has been updated and replaced by NICE technology appraisal guidance 504.
This guidance has been replaced by NICE technology appraisal guidance 91.
This guidance has been updated and replaced by NICE technology appraisal guidance 375.
Baloxavir marboxil for treating influenza in babies under 1 year [ID6555]
Discontinued Reference number: GID-TA11712
Baloxavir marboxil for treating and preventing influenza in people 3 weeks to 11 years [ID6554]
In development Reference number: GID-TA11732 Expected publication date: TBC
Intramedullary distraction for lower limb lengthening (IPG197)
This guidance has been updated and replaced by NICE HealthTech guidance 613.
This guidance has been updated and replaced by the NICE guideline on asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN).
Parent-training/education programmes in the management of children with conduct disorders (TA102)
This guidance has been updated and replaced by NICE guideline CG158.
Dexamethasone intravitreal implant for treating diabetic macular oedema (TA349)
This guidance has been updated and replaced by NICE technology appraisal guidance 824.
Guidance on the use of etanercept for the treatment of juvenile idiopathic arthritis (TA35)
This guidance has been updated and replaced by NICE technology appraisal guidance 373.
This guidance has been updated and replaced by the NICE guideline on asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN).
This guidance has been updated and replaced by NICE technology appraisal guidance 908.
This guidance has been withdrawn because Novartis has discontinued ofatumumab (Arzerra). Ofatumumab will continue to be available for people who need it. Contact Clinigen at managedacess@clinigengroup.com or 01932 842100 for details.
Ruxolitinib for treating polycythaemia vera (terminated appraisal) (TA356)
This guidance has been updated and replaced by NICE technology appraisal guidance TA921.
This guidance has been updated and replaced by NICE technology appraisal guidance 476.
The appraisal has been withdrawn because Janssen withdrew their marketing authorisation on 1 May 2018. The availability of direct-acting antiviral combination treatments for hepatitis C has reduced the use of simeprevir, so the company has decided to discontinue it.
This guidance has been withdrawn because Bristol-Myers Squibb has discontinued daclatasvir (Daklinza).
Apremilast for treating moderate to severe plaque psoriasis (TA368)
This guidance has been updated and replaced by NICE technology appraisal guidance 419. The clinical effectiveness and cost effectiveness of rituximab for follicular lymphoma (TA37)
This guidance has been updated and replaced by NICE technology appraisal guidance 137.
This guidance has been updated and replaced by NICE technology appraisal guidance 433.
Radium-223 dichloride for treating hormone-relapsed prostate cancer with bone metastases (TA376)
This guidance has been updated and replaced by NICE technology appraisal guidance 412.
This guidance has been updated and replaced by NICE guideline PH10.
This guidance has been updated and replaced by NICE technology appraisal guidance 427.
This guidance has been withdrawn.
Clopidogrel in the treatment of non-ST-segment-elevation acute coronary syndrome (TA80)
This guidance has been replaced by recommendations 1.3.4 to 1.3.8 in NICE guideline CG94 and by recommendation 1.3.18 in NICE guideline CG172.
Selpercatinib for treating advanced thyroid cancer with RET alterations (TA742)
This guidance has been updated and replaced by NICE technology appraisal guidance 1038.
Crizanlizumab for preventing sickle cell crises in sickle cell disease (TA743)
NICE has withdrawn this guidance. Novartis will stop marketing crizanlizumab (Adakveo) because its marketing authorisation has been withdrawn by the Medicines and Healthcare products Regulatory Agency (MHRA). Novartis has issued a direct letter to healthcare professionals specialising in haematology. No new people will start taking crizanlizumab in the UK. Healthcare professionals should discuss alternative treatment options with people currently having crizanlizumab.
Fedratinib for treating disease-related splenomegaly or symptoms in myelofibrosis (TA756)
This guidance has been updated and replaced by NICE technology appraisal guidance 1018.
Fostamatinib for treating refractory chronic immune thrombocytopenia (TA759)
This guidance has been updated and replaced by NICE technology appraisal guidance 835.
This guideline has been updated and replaced by NICE guideline CG137.
Selpercatinib for previously treated RET fusion-positive advanced non-small-cell lung cancer (TA760)
This guidance has been updated and replaced by NICE technology appraisal guidance TA1042
This guidance has been updated and replaced by NICE technology appraisal guidance 1043.
This guidance has been updated and replaced by NICE technology appraisal guidance 1040.
This guidance has been updated and replaced by NICE technology appraisal guidance 1075.
The clinical effectiveness and cost effectiveness of anakinra for rheumatoid arthritis (TA72)
This appraisal has been updated and replaced by NICE guideline CG79.
This guidance has been updated and replaced by NICE technology appraisal guidance 1110.
This guidance has been updated and replaced by NICE technology appraisal guidance 887.
Atezolizumab for adjuvant treatment of resected non-small-cell lung cancer (TA823)
This guidance has been updated and replaced by NICE technology appraisal guidance 1071.
This guideline has been updated and replaced by NICE guideline CG137.